KRTAP4-2 and ITGB4

Data Source:
BioGRID (two hybrid)

		KRTAP4-2	ITGB4
Description		keratin associated protein 4-2	integrin subunit beta 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Basement Membrane Nucleolus Plasma Membrane Focal Adhesion Integrin Complex Basal Plasma Membrane Cell Surface Cell Junction Hemidesmosome Cell Leading Edge Nuclear Membrane Receptor Complex Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	G Protein-coupled Receptor Binding Integrin Binding Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding
	Biological Process	Keratinization	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Peripheral Nervous System Myelin Formation Cell Adhesion Mediated By Integrin Nail Development Skin Morphogenesis Filopodium Assembly Mesodermal Cell Differentiation Cell Motility Trophoblast Cell Migration
Pathways		Keratinization	Assembly of collagen fibrils and other multimeric structures Laminin interactions Syndecan interactions Type I hemidesmosome assembly
Drugs			R1295
Diseases			Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS
Interacting Genes		124 interacting genes: ADAMTSL4 ALDH3B1 AMOTL2 ANKS1A AQP1 ATG9A AVPI1 AXIN1 BAG4 BYSL CATSPER1 CCER1 CELF5 CHIC2 CHRD CRCT1 CREB5 CRY2 CYP21A2 CYSRT1 DLGAP2 DOCK2 FAM74A4 GLRX3 GNMT GUCD1 HOXA1 HOXB9 HPCAL1 HSD3B7 ITGB4 KPRP KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP26-1 KRTAP3-3 KRTAP4-4 KRTAP4-5 KRTAP5-2 KRTAP5-3 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAFB MEOX2 NBPF19 NECTIN3 NLK NOTCH2NLA NR1D2 NR4A3 NTAQ1 NUFIP2 OTX1 OXER1 PDE9A PGLS PHLDA1 PIN1 PLSCR1 PLSCR4 POM121L8P POU4F2 PRKAB2 PRKAG1 PSMA6 RASSF5 RGS20 SDC3 SHFL SLC23A1 SLC25A10 SMCP SPATA24 SPATA3 SPRY1 TCEANC TINAGL1 TRIM42 TXNDC5 TYRO3 VASN VGLL3 YY1 ZBTB24 ZNF124 ZNF20 ZNF417 ZNF559 ZNF581 ZNF688	59 interacting genes: ADAMTSL4 ALOX12 APPBP2 ATXN1 CLCA1 CLCA2 COL17A1 CYSRT1 DST ECM1 EIF6 ERBB2 ERBIN FYN GRB2 HOXA1 ITGA6 KPRP KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP4-2 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 MDFI MET MID2 MTUS2 MYF5 NBPF19 NOTCH2NLA PLEC PLSCR4 POU2AF1 PRKCA PRKCD PTK2 SDC2 SDC3 SHC1 SREBF2 TGM1 TRIP6 VIM YES1 YWHAB YWHAQ
Entrez ID		85291	3691
HPRD ID		13944	00946
Ensembl ID		ENSG00000244537	ENSG00000132470
Uniprot IDs		Q9BYR5	A0A024R8K7 A0A024R8N2 A0A024R8T0 B7ZLD8 P16144
PDB IDs			1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A 4Q58 4WTW 4WTX 6GVK 6GVL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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