DGKD and MYH2

Data Source:
HPRD (in vitro)

		DGKD	MYH2
Description		diacylglycerol kinase delta	myosin heavy chain 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit	Cytosol Muscle Myosin Complex Cell-cell Junction Myofibril Sarcomere Myosin Filament Protein-containing Complex
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Binding Diacylglycerol Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Endocytosis Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Response To Organic Substance Protein Transport Second-messenger-mediated Signaling Platelet Activation Intracellular Signal Transduction Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Diacylglycerol Metabolic Process Lipid Phosphorylation Negative Regulation Of Protein Kinase C Signaling Positive Regulation Of Clathrin-dependent Endocytosis	Muscle Contraction Muscle Filament Sliding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways		Effects of PIP2 hydrolysis	Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs		Phosphatidyl serine alpha-Tocopherol succinate
Diseases
GWAS		Bilirubin levels ( 20639394 32084209) Calcium levels ( 24068962 29403010 20705733) Crohn's disease ( 22412388) Glaucoma (primary open-angle) ( 29891935) Kidney stones ( 31729369) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Total body bone mineral density ( 29304378) Type 2 diabetes ( 32499647 30718926) Urinary calcium excretion ( 31993563)
Interacting Genes		8 interacting genes: DGKH DYSF HAX1 IGSF21 MYH2 PRKCA SREK1 TNFRSF14	7 interacting genes: AMPD1 DGKD DUX4L9 OBSCN PRKCE PTK2B S100A4
Entrez ID		8527	4620
HPRD ID		03492	01173
Ensembl ID		ENSG00000077044	ENSG00000125414
Uniprot IDs		A0A024R495 Q16760	Q9UKX2
PDB IDs		1R79 3BQ7
Enriched GO Terms of Interacting Partners?
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