ELP1 and ELP3

Data Source:
BioGRID (biochemical, affinity chromatography technology, pull down, biochemical, affinity chromatography technology)

		ELP1	ELP3
Description		elongator acetyltransferase complex subunit 1	elongator acetyltransferase complex subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Elongator Holoenzyme Complex	Nucleus Nucleolus Cytoplasm Cytosol Elongator Holoenzyme Complex
	Molecular Function	TRNA Binding Protein Binding	TRNA Binding Protein Binding N-acetyltransferase Activity Phosphorylase Kinase Regulator Activity Acetyltransferase Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding TRNA Uridine(34) Acetyltransferase Activity
	Biological Process	TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation	Neuron Migration TRNA Wobble Uridine Modification TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Positive Regulation Of Cell Migration Regulation Of Protein Kinase Activity
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005 26604143) Malaria ( 31844061) Systemic lupus erythematosus ( 28714469)
Interacting Genes		25 interacting genes: BAG6 BARD1 CCT5 CDKN2B CHUK CSTF2 ELP3 HTT IKBKB IRF4 MAN2A2 MAP3K14 MAP3K7 MAPK8 MRPL42 NDUFB9 NFKBIA NIPSNAP3A PBX2 PLP2 SDHAF2 SNAPIN TAC3 TTR TXNDC9	6 interacting genes: CTDP1 ELP1 H3C14 H4C1 SMAD1 SMURF1
Entrez ID		8518	55140
HPRD ID		04763	10936
Ensembl ID		ENSG00000070061	ENSG00000134014
Uniprot IDs		A0A6Q8PF66 A0A6Q8PGW3 A0A6Q8PHC9 B3KNB2 B4E3I9 F5H2T0 O95163 Q4LE38 Q8N516	B4DKA4 B4DXV1 Q9H9T3
PDB IDs		5CQR
Enriched GO Terms of Interacting Partners?
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