SMIM3 and ATP1B4

Data Source:
BioGRID (two hybrid)

		SMIM3	ATP1B4
Description		small integral membrane protein 3	ATPase Na+/K+ transporting family member beta 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nuclear Envelope Nuclear Inner Membrane Integral Component Of Plasma Membrane Sodium:potassium-exchanging ATPase Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Inorganic Cation Transmembrane Transporter Activity
	Biological Process		Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inorganic Cation Transmembrane Transport
Pathways			SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)	Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1	7 interacting genes: ASGR1 C3orf52 CSGALNACT2 CXCL9 ERMP1 SMIM3 TSPAN2
Entrez ID		85027	23439
HPRD ID		12212	06453
Ensembl ID		ENSG00000256235	ENSG00000101892
Uniprot IDs		Q9BZL3	Q9UN42
PDB IDs
Enriched GO Terms of Interacting Partners?
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