CEP19 and PTPN23

Data Source:
BioGRID (two hybrid)

		CEP19	PTPN23
Description		centrosomal protein 19	protein tyrosine phosphatase non-receptor type 23
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Cilium Ciliary Basal Body	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Nuclear Body Ciliary Basal Body Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding
	Biological Process	Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	Negative Regulation Of Epithelial Cell Migration Protein Transport Endocytic Recycling Peptidyl-tyrosine Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Early Endosome To Late Endosome Transport Cilium Assembly Positive Regulation Of Wnt Protein Secretion Cellular Response To Cytokine Stimulus Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways			Interleukin-37 signaling
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738)	C-reactive protein levels ( 30388399) Refractive error ( 32231278) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		50 interacting genes: AK4 ANAPC15 C4orf19 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CEP350 CEP43 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2A RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81	11 interacting genes: ALG2 CEP19 CEP55 CHMP4B DDX24 LRRK2 NOTCH2NLA PSMA3 TRIM27 UBAP1 UBC
Entrez ID		84984	25930
HPRD ID		17488	05959
Ensembl ID		ENSG00000174007	ENSG00000076201
Uniprot IDs		Q96LK0	B4DST5 Q9H3S7
PDB IDs			3RAU 5CRU 5CRV 5LM1 5LM2 5MJY 5MJZ 5MK0 5MK1 5MK2 5MK3
Enriched GO Terms of Interacting Partners?
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