PPFIBP1 and S100A4

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		PPFIBP1	S100A4
Description		PPFIA binding protein 1	S100 calcium binding protein A4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Presynaptic Active Zone	Extracellular Region Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Cell Adhesion Neuromuscular Junction Development Synapse Organization	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Receptor-type tyrosine-protein phosphatases
Drugs			Trifluoperazine Copper
Diseases
GWAS		Cerebral cortical growth ( 29682794) Early-onset Parkinson's disease ( 28256260) Refractive error ( 32231278)	Blood protein levels ( 29875488) Pulse pressure ( 30578418)
Interacting Genes		8 interacting genes: PBX2 PPFIA1 PPFIA2 PPFIA3 PTPRM S100A4 YWHAG YWHAQ	28 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119
Entrez ID		8496	6275
HPRD ID		04390	15914
Ensembl ID		ENSG00000110841	ENSG00000196154
Uniprot IDs		A0A024RB02 Q86W92	P26447
PDB IDs			1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58
Enriched GO Terms of Interacting Partners?
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