PRPF38A and GTF3C1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRPF38A	GTF3C1
Description		pre-mRNA processing factor 38A	general transcription factor IIIC subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Transcription Factor TFIIIC Complex Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		mRNA Splicing - Major Pathway	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS			Asthma ( 31959851) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		24 interacting genes: AP2M1 APP CHERP CLK1 CLK2 CSNK2A1 DHX8 DVL3 GTF3C1 JMJD6 MAPK6 POLA2 PPIG PRMT5 RBM39 RNPS1 SDCBP SDCBP2 SRPK1 SRPK2 SRSF4 SRSF7 U2AF1 ZCCHC10	23 interacting genes: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 PRPF38A RBM23 SNU13 SUMO2 SUPT5H TBC1D17 UBE3A
Entrez ID		84950	2975
HPRD ID		10972	07540
Ensembl ID		ENSG00000134748	ENSG00000077235
Uniprot IDs		Q8NAV1	Q12789
PDB IDs		4RZ9 4RZA 5F5S 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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