SLC35B4 and PVR

Data Source:
BioGRID (two hybrid)

		SLC35B4	PVR
Description		solute carrier family 35 member B4	PVR cell adhesion molecule
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane	Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Integral Component Of Membrane
	Molecular Function	UDP-N-acetylglucosamine Transmembrane Transporter Activity UDP-xylose Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity	Virus Receptor Activity Protein Binding Signaling Receptor Activity Cell Adhesion Molecule Binding
	Biological Process	Regulation Of Gluconeogenesis Carbohydrate Transport UDP-xylose Transmembrane Transport UDP-N-acetylglucosamine Transmembrane Transport	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Regulation Of Immune Response Susceptibility To T Cell Mediated Cytotoxicity
Pathways		Transport of nucleotide sugars	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization
Drugs			Sphingosine Myristic acid
Diseases
GWAS		Mean platelet volume ( 32888494 27863252) Plateletcrit ( 32888494) Systolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)	Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 32888494 27863252) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet distribution width ( 32888494)
Interacting Genes		32 interacting genes: AQP6 CD79A CISD2 CLDN5 CPLX4 CREB3L1 EBAG9 ERGIC3 ERP29 FAM209A FAM210B FFAR2 GPR152 GPX8 HSD17B13 KASH5 LHFPL5 LMNA MMGT1 MUC1 PDZK1IP1 PVR RHBDL2 SCARA5 SLC18A1 STOM TBXA2R TMEM130 TMEM237 TMEM52B TYROBP VSIR	69 interacting genes: ADIPOQ ANKRD46 AP1M2 AQP10 BRICD5 C3orf52 CD226 CD47 CD96 CLDN19 CTXN3 CYB561A3 CYHR1 CYSRT1 DYNLT1 DYNLT3 EBP EDDM3B GPRC5D HHATL HOXA1 INSIG2 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-1 KRTAP3-3 KRTAP6-3 KRTAP9-3 MFSD11 NBPF19 NECTIN1 NECTIN3 NINJ1 NINJ2 NOTCH2NLA OLFM4 PGA4 PLA2G3 PLP2 PLPP6 RUSF1 SCD SFTPC SLC30A2 SLC35B4 SLC41A2 SMIM1 SNAP47 SYS1 TAS2R19 TIGIT TM6SF2 TMBIM6 TMEM147 TMEM229B TMEM54 TMEM65 TMEM79 TSPO VAMP5 VTN WNK1 ZDHHC15 ZDHHC22 ZFPL1
Entrez ID		84912	5817
HPRD ID		11578	01434
Ensembl ID		ENSG00000205060	ENSG00000073008
Uniprot IDs		Q969S0	A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151
PDB IDs			1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O
Enriched GO Terms of Interacting Partners?
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