RTN4IP1 and SORBS1

Data Source:
BioGRID (two hybrid)

		RTN4IP1	SORBS1
Description		reticulon 4 interacting protein 1	sorbin and SH3 domain containing 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane	Stress Fiber Nucleus Centrosome Cytosol Plasma Membrane Adherens Junction Zonula Adherens Focal Adhesion Nuclear Matrix Cell-substrate Junction Membrane Raft
	Molecular Function	Protein Binding Zinc Ion Binding Oxidoreductase Activity	Actin Binding Insulin Receptor Binding Protein Binding Cytoskeletal Protein Binding Signaling Receptor Complex Adaptor Activity
	Biological Process	Nervous System Development Regulation Of Dendrite Development	Muscle Contraction Cell-matrix Adhesion Insulin Receptor Signaling Pathway Cellular Response To Insulin Stimulus Stress Fiber Assembly Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Import Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Lipid Biosynthetic Process Focal Adhesion Assembly Positive Regulation Of Protein Localization To Plasma Membrane
Pathways			Smooth Muscle Contraction
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483)	Diabetic nephropathy in type 1 diabetes ( 25476525) Estimated glomerular filtration rate ( 31152163) Hematocrit ( 32888494) Mean platelet volume ( 32888494) Obesity-related traits ( 23251661) PR interval ( 30046033 32439900) Red blood cell count ( 32888494) Staphylococcus aureus nasal carriage (persistent) ( 26569114) Suicide risk ( 21041247)
Interacting Genes		23 interacting genes: ARFGAP3 CALCOCO2 CBFA2T3 CENPK CTAG1A CTAG1B ERMN EXOC7 GGA2 HDX MARCHF5 PPP1R8 PYM1 RELA RTN4 RTN4R RUNX1T1 SCAF1 SMURF2 SORBS1 WBP11 WWTR1 ZYX	27 interacting genes: ABI1 ABL1 ACTA1 ADAM15 AFDN CBL CDK6 EFNB1 FLOT1 INPPL1 INSM1 INSR KHDRBS1 MAP4K3 PAK2 PGR PILRA PTK2 PXN RPL4 RTN4IP1 SEMA6A SH2B2 SLC10A3 SRC TENM1 VCL
Entrez ID		84816	10580
HPRD ID		18008	05587
Ensembl ID		ENSG00000130347	ENSG00000095637
Uniprot IDs		Q8WWV3	B4DTX5 Q9BX66
PDB IDs		2VN8	2DL3 2ECZ 2LJ0 2LJ1 2MOX 2O2W 2O31 2O9S 2O9V 4LN2 4LNP
Enriched GO Terms of Interacting Partners?
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