HIRIP3 and HIRA

Data Source:
HPRD (in vitro, in vivo)

		HIRIP3	HIRA
Description		HIRA interacting protein 3	histone cell cycle regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	HIR Complex Chromatin Nucleus Nucleoplasm PML Body Protein-containing Complex Extracellular Exosome
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Factor Binding Protein Binding Nucleosome Binding Histone Binding
	Biological Process	Chromatin Assembly Or Disassembly	DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Negative Regulation Of Transcription, DNA-templated
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 25056061 29483656)	Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		11 interacting genes: ABCF3 APP CSNK2A1 CSNK2B H2BC21 H3-4 H4C1 HIRA SGK2 SRPK1 SRPK2	16 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 TRIM55 TRIM63 UBE2I UPF1
Entrez ID		8479	7290
HPRD ID		04531	02583
Ensembl ID		ENSG00000149929	ENSG00000100084
Uniprot IDs		Q9BW71	P54198
PDB IDs			2I32 5YJE
Enriched GO Terms of Interacting Partners?
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