MYPN and NEBL

Data Source:
HPRD (two hybrid)

		MYPN	NEBL
Description		myopalladin	nebulette
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Z Disc Axon I Band	Stress Fiber Z Disc I Band Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Sarcomere Organization Dendrite Self-avoidance	Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737) Chronic kidney disease ( 31152163) Coffee consumption ( 31046077) Creatine kinase levels ( 29403010) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate ( 29403010) Height ( 25282103) Lung function (FVC) ( 28166213 30804560) Optic nerve measurement (disc area) ( 20395239) Peak expiratory flow ( 30804560) Psoriasis ( 25854761)	Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Atrial fibrillation ( 28416822) Coronary artery aneurysm in Kawasaki disease ( 27171184) Heel bone mineral density ( 30598549) Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis ( 28388302) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Photic sneeze reflex ( 27182965) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Plasma anti-thyroid peroxidase levels ( 29678681) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Sporadic pituitary adenoma ( 26029870) Urate levels in lean individuals ( 25811787) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference ( 28552196)
Interacting Genes		8 interacting genes: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL PDLIM3 TTN	34 interacting genes: ACAP1 ACTB ACTN1 ACTN3 CCDC125 CCDC136 CEP70 FAM9B GMCL1 GOLGA2 GOLGA6A HOMER3 KIFC3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PIBF1 PIK3R3 PRKAB2 QARS1 SPAG5 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 VCL XIRP1 XIRP2 ZDHHC17 ZGPAT ZYX
Entrez ID		84665	10529
HPRD ID		10536	10403
Ensembl ID		ENSG00000138347	ENSG00000078114
Uniprot IDs		A0A087WX60 Q86TC9	O76041 Q59FZ8
PDB IDs			4F14
Enriched GO Terms of Interacting Partners?
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