DOC2A and TGFB1I1

Data Source:
BioGRID (affinity chromatography technology)

		DOC2A	TGFB1I1
Description		double C2 domain alpha	transforming growth factor beta 1 induced transcript 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding
	Biological Process	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion	Cell Adhesion Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)	Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B	29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL
Entrez ID		8448	7041
HPRD ID		05195	03831
Ensembl ID		ENSG00000149927	ENSG00000140682
Uniprot IDs		Q14183	A0A024QZE7 O43294
PDB IDs		4MJJ
Enriched GO Terms of Interacting Partners?
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