GNPAT and RAB35

Data Source:
HPRD (two hybrid)

		GNPAT	RAB35
Description		glyceronephosphate O-acyltransferase	RAB35, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane Mitochondrial Membrane	Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Clathrin-coated Vesicle Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Glycerone-phosphate O-acyltransferase Activity	GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding
	Biological Process	Protein Targeting To Peroxisome Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Synapse Assembly Response To Nutrient Ether Lipid Biosynthetic Process Phospholipid Biosynthetic Process Cerebellum Morphogenesis Paranodal Junction Assembly Response To Drug Response To Starvation Membrane Organization Response To Fatty Acid	Mitotic Cytokinesis Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways		Synthesis of PA Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import	TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS			Heel bone mineral density ( 30598549)
Interacting Genes		6 interacting genes: AGPS GPR3 HSPB1 PEX5 RAB35 VDR	9 interacting genes: APP CALCOCO2 CBR3 GNPAT IDH3B PTPRS TBPL1 TRIM54 WDCP
Entrez ID		8443	11021
HPRD ID		04120	05010
Ensembl ID		ENSG00000116906	ENSG00000111737
Uniprot IDs		O15228	Q15286
PDB IDs			3TW8 6EKK 6IF2 6IF3
Enriched GO Terms of Interacting Partners?
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