UQCC2 and NRDE2

Data Source:
BioGRID (two hybrid)

		UQCC2	NRDE2
Description		ubiquinol-cytochrome c reductase complex assembly factor 2	NRDE-2, necessary for RNA interference, domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Nuclear Body Mitochondrial Nucleoid	Nucleoplasm Nucleolus Nuclear Speck
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Regulation Of Insulin Secretion Positive Regulation Of Mitochondrial Translation Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Skeletal Muscle Cell Differentiation	RNA Interference Heterochromatin Assembly By Small RNA Positive Regulation Of RNA Export From Nucleus Negative Regulation Of RNA Catabolic Process
Pathways
Drugs
Diseases
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gait speed in old age ( 28077804) Hodgkin's lymphoma ( 30194254)	Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		15 interacting genes: CDKN2D CEACAM5 EXOC8 GNG13 GRB2 HSPB1 MKRN3 MRFAP1 NRDE2 RABGAP1L SNAP25 TRAPPC2 TRAPPC2B TXN2 ZNF765	11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28
Entrez ID		84300	55051
HPRD ID		12847	12625
Ensembl ID		ENSG00000137288	ENSG00000119720
Uniprot IDs		Q9BRT2	Q9H7Z3
PDB IDs			6IEH
Enriched GO Terms of Interacting Partners?
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