UTP23 and NHP2

Data Source:
BioGRID (pull down)

		UTP23	NHP2
Description		UTP23 small subunit processome component	NHP2 ribonucleoprotein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Small-subunit Processome	Chromosome, Telomeric Region Nucleoplasm Telomerase Holoenzyme Complex Sno(s)RNA-containing Ribonucleoprotein Complex Box H/ACA SnoRNP Complex Box H/ACA ScaRNP Complex Box H/ACA Telomerase RNP Complex
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding MRNA 5'-UTR Binding Small Ribosomal Subunit RRNA Binding	RNA Binding Protein Binding Box H/ACA SnoRNA Binding Telomerase RNA Binding
	Biological Process	Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)	Cleavage Involved In RRNA Processing Maturation Of LSU-rRNA Telomere Maintenance Via Telomerase RRNA Pseudouridine Synthesis SnRNA Pseudouridine Synthesis Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways			Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol
Drugs
Diseases			Dyskeratosis congenita (DC), including: X-linked dyskeratosis congenita (DKCX); Autosomal dominant dyskeratosis congenita (DKCA1); Autosomal recessive dyskeratosis congenita (DKCB1)
GWAS			Platelet count ( 29403010)
Interacting Genes		31 interacting genes: APP CYSRT1 DDX52 FCF1 GOLGA2 GRN KRT31 KRT34 KRT38 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 MEOX2 MID2 NBPF19 NFKBID NHP2 NOTCH2NLA PDE9A RRP7A SNHG3 TCF4 TEPSIN TRAF2 TRIB3 TRIM23 TRIM27	9 interacting genes: IKBKG JMJD6 MYL2 NEDD4 NEDD4L NOP10 NOS1AP PRNP UTP23
Entrez ID		84294	55651
HPRD ID		17499	07570
Ensembl ID		ENSG00000147679	ENSG00000145912
Uniprot IDs		Q9BRU9	J3QSY4 Q9NX24
PDB IDs
Enriched GO Terms of Interacting Partners?
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