PCGF6 and MAGEL2

Data Source:
BioGRID (two hybrid)

		PCGF6	MAGEL2
Description		polycomb group ring finger 6	MAGE family member L2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleus Endosome Early Endosome Cytosol Retromer Complex
	Molecular Function	Protein Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Actin Nucleation Protein K63-linked Ubiquitination
Pathways		Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)	Menarche (age at onset) ( 25231870) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		26 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RING1 RNF2 SS18L1 TRIM14 TRIM55 TRIM63 TULP3 UBE2D3 UBE2U USP2 USP21	6 interacting genes: FHL2 IRS4 PCGF6 RNF41 SUFU VPS52
Entrez ID		84108	54551
HPRD ID		07427	12008
Ensembl ID		ENSG00000156374	ENSG00000254585
Uniprot IDs		Q9BYE7	Q9UJ55
PDB IDs		2DJB
Enriched GO Terms of Interacting Partners?
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