RIOK1 and FBXO6

Data Source:
BioGRID (unspecified method)

		RIOK1	FBXO6
Description		RIO kinase 1	F-box protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Preribosome, Small Subunit Precursor Methyltransferase Complex	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Hydrolase Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Carbohydrate Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Phosphorylation Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Positive Regulation Of RRNA Processing	DNA Damage Checkpoint Protein Polyubiquitination DNA Repair Proteolysis Glycoprotein Catabolic Process Response To Unfolded Protein Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Fostamatinib
Diseases
GWAS		Response to fenofibrate (triglyceride levels) ( 27002377)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
Interacting Genes		7 interacting genes: APP CSNK2A1 FBXO6 KDM1A SETD7 WDR77 YWHAB	3 interacting genes: ORC4 RIOK1 SKP1
Entrez ID		83732	26270
HPRD ID		17978	07291
Ensembl ID		ENSG00000124784	ENSG00000116663
Uniprot IDs		Q9BRS2	Q9NRD1
PDB IDs		4OTP 6G5I 6V0N
Enriched GO Terms of Interacting Partners?
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