USP9Y and PACS1

Data Source:
HPRD (in vitro)

		USP9Y	PACS1
Description		ubiquitin specific peptidase 9 Y-linked	phosphofurin acidic cluster sorting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Golgi Apparatus Cytosol COPI-coated Vesicle
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Cysteine-type Peptidase Activity Co-SMAD Binding	Protein Binding Ion Channel Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Spermatogenesis Cell Migration Protein Deubiquitination Protein Phosphopantetheinylation BMP Signaling Pathway	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane
Pathways			Nef mediated downregulation of MHC class I complex cell surface expression
Drugs
Diseases		Azoospermia, including: Azoospermia; Azoospermia due to perturbations of meiosis
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006)
Interacting Genes		2 interacting genes: MAPT UBC	10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4
Entrez ID		8287	55690
HPRD ID		02449	06320
Ensembl ID		ENSG00000114374	ENSG00000175115
Uniprot IDs		O00507	A0A024R5H6 Q6VY07
PDB IDs
Enriched GO Terms of Interacting Partners?
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