NAA10 and CASP8AP2

Data Source:
BioGRID (two hybrid)

		NAA10	CASP8AP2
Description		N-alpha-acetyltransferase 10, NatA catalytic subunit	caspase 8 associated protein 2
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex	Nucleus Nucleoplasm Cytoplasm Mitochondrion PML Body
	Molecular Function	Peptide Alpha-N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Acetyltransferase Activity Ribosome Binding Peptide-serine-N-acetyltransferase Activity Peptide-glutamate-N-acetyltransferase Activity	Transcription Corepressor Activity Death Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Peptidase Activator Activity Involved In Apoptotic Process SUMO Polymer Binding
	Biological Process	DNA Packaging Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation N-terminal Peptidyl-serine Acetylation N-terminal Peptidyl-glutamic Acid Acetylation Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Cycle Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Fas Signaling Pathway Negative Regulation Of Transcription, DNA-templated Cellular Response To Mechanical Stimulus Apoptotic Signaling Pathway
Pathways			SUMOylation of transcription cofactors
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Diseases
GWAS		Systemic lupus erythematosus ( 26502338)	Asthma ( 31959851) Estimated glomerular filtration rate in non-diabetics ( 31451708) Major depressive disorder ( 29317602)
Interacting Genes		55 interacting genes: ACOT12 BAALC BCOR CALCOCO2 CASP8AP2 CCDC106 CCDC174 CDC25A CDCA5 CEP44 CREB3 CREBRF DDIT4L DHX57 EHMT2 FIP1L1 GPATCH2L HIF1A HIF1AN HSPA4 KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 MCRS1 MDM4 MEOX2 MKRN1 MRPS11 NAA15 NAA16 NAA50 NAT1 NAT2 NOXA1 PDE4DIP PGK1 PLSCR3 PPP2R3B PSME2 RAB3IP RBCK1 RCN3 RIMBP2 RPL26 SEMA3B SNX33 SSX2IP TAF7L TSEN54 UBC ZBTB14 ZNF202 ZNF655	19 interacting genes: CALM1 CASP10 CASP8 CREBBP CREM CTBP2 FADD FAS GLUL MX1 NAA10 NR3C2 PML SP100 SREBF2 TCL1A TRAF2 TRIM21 UBE2I
Entrez ID		8260	9994
HPRD ID		02056	06048
Ensembl ID		ENSG00000102030	ENSG00000118412
Uniprot IDs		B7Z9N2 P41227	Q9UKL3
PDB IDs		6C95 6C9M 6PPL 6PW9	2LR8 6ANO 6AOZ 6AP0
Enriched GO Terms of Interacting Partners?
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