COIL and KLHL42

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COIL	KLHL42
Description		coilin	kelch like family member 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body	Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly	Protein Polyubiquitination Cell Cycle Regulation Of Microtubule-based Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Cell Division
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Height ( 18391951)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959) Height ( 31562340) Osteoarthritis (hip) ( 30664745) Refractive error ( 32231278) Resting heart rate ( 27798624) Type 2 diabetes ( 30054458)
Interacting Genes		83 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MFAP1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277	35 interacting genes: ADD1 ANKRD33 CALCOCO2 CDCA4 CKMT2 COIL CT55 CUL3 DAZAP2 DDI1 FAM168A INCA1 KRTAP19-4 MYOG OIP5 OSTF1 P4HB PFDN5 POMC RCN3 REL SERTAD1 SERTAD3 SSX2IP STAM2 STXBP4 TRIM23 TRIM54 TTC23 UBE2E3 UBQLN1 UBQLN2 UBQLN4 USHBP1 VPS52
Entrez ID		8161	57542
HPRD ID		02605	17237
Ensembl ID		ENSG00000121058	ENSG00000087448
Uniprot IDs		P38432	B2RNT7 F5H523 Q9P2K6
PDB IDs
Enriched GO Terms of Interacting Partners?
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