CYB5B and COG8

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CYB5B	COG8
Description		cytochrome b5 type B	component of oligomeric golgi complex 8
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex	Golgi Membrane Golgi Apparatus Membrane Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity Electron Transfer Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity	Protein Binding
	Biological Process	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Electron Transport Chain Regulation Of Catalytic Activity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport
Pathways		Phase I - Functionalization of compounds	COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs		Phenethyl Isothiocyanate
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		48 interacting genes: AHNAK2 APP AQP6 BIK BNIP3L BTNL9 CD33 CD79A CGRRF1 CLDN7 CLN8 CPLX4 CREB3 EBP FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PLPP4 REEP4 RETREG3 SDHAF4 SLC10A6 SLC16A2 SLC39A9 STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B	4 interacting genes: GEM HGS MTNR1B MYEF2
Entrez ID		80777	84342
HPRD ID		13106	07374
Ensembl ID		ENSG00000103018	ENSG00000213380
Uniprot IDs		O43169	A0A024R6Z6 Q96MW5
PDB IDs		3NER
Enriched GO Terms of Interacting Partners?
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