PBX4 and ZNF330

Data Source:
BioGRID (two hybrid)

		PBX4	ZNF330
Description		PBX homeobox 4	zinc finger protein 330
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin XY Body Nucleus	Chromosome, Centromeric Region Nucleus Nucleolus Midbody
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Animal Organ Morphogenesis Positive Regulation Of Transcription, DNA-templated Embryonic Organ Development Neuron Development	Biological_process
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder symptom score ( 27663945) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Cholesterol, total ( 20686565) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) LDL cholesterol ( 18193044 19060906 20686565) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Obesity-related traits ( 23251661) Perceived unattractiveness to mosquitoes ( 28199695) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Schizophrenia ( 25056061 29483656 23974872) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Total cholesterol levels ( 30275531) Triglyceride levels (parental genotype effect) ( 30255771) Triglyceride levels in response to fenofibrate treatment (parental genotype effect) ( 30255771) Triglycerides ( 18193044 19060906 20686565)	Conduct disorder ( 20585324) Malaria ( 31844061)
Interacting Genes		65 interacting genes: ARHGEF3 BCL6 BFSP2 C14orf119 C1orf109 CCM2L CDKN2C CHCHD2 CLCNKA CPNE7 EIF1AD EIF3B EIF3F EXOC8 GADD45GIP1 GEM GINS4 GPANK1 HOXB2 HOXB5 HOXC5 HOXC8 HOXD4 HSBP1L1 IFT20 IPO13 KDM1A KLHL38 LMO2 MAGOHB MAPK9 MBD3 MEIS2 MIPOL1 NCK2 NEK6 NUTF2 OSTF1 PACSIN2 PICK1 PIH1D2 PIK3R3 PKNOX1 PKNOX2 PPL RANBP3 RBX1 RIPPLY1 RIPPLY2 SCNM1 SERTAD1 SMARCD1 SPANXN2 SPANXN3 SPG21 TFIP11 TRIM41 TSEN15 TSSK3 TXNDC9 UBTFL1 USHBP1 USP20 WWOX ZNF330	52 interacting genes: ADAMTSL4 CCDC33 CCN3 CFP CHIC2 CNNM3 CREB5 CYSRT1 KLF15 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP13-3 KRTAP5-7 MDFI MEOX2 NBPF19 NDUFB7 NOTCH2NLA NR4A3 OTX1 PBX4 PICK1 RBAK RSPO2 RSPO4 RWDD4 SPATA3 SPRY1 STK16 STX19 SUFU TCL1B TLE5 TRIM42 ZBTB42 ZNF23 ZNF250 ZNF408 ZNF426 ZNF440 ZNF460 ZNF547 ZNF587 ZNF655 ZNF664 ZNF669 ZNF683 ZNF688 ZNF764 ZNF768 ZNF837
Entrez ID		80714	27309
HPRD ID		16287	15775
Ensembl ID		ENSG00000105717	ENSG00000109445
Uniprot IDs		Q9BYU1	B4DFG9 Q53EN0 Q9Y3S2
PDB IDs
Enriched GO Terms of Interacting Partners?
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