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TSGA10 and CDC73
Data Source:
BioGRID
(two hybrid, two hybrid)
TSGA10
CDC73
Description
testis specific 10
cell division cycle 73
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Cytoplasm
Centriole
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytosol
Cdc73/Paf1 Complex
Molecular Function
Molecular_function
Protein Binding
RNA Polymerase II Complex Binding
Protein Binding
Biological Process
Spermatogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Endodermal Cell Fate Commitment
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
MRNA Polyadenylation
Cell Cycle
Negative Regulation Of Cell Population Proliferation
Histone Monoubiquitination
Wnt Signaling Pathway
Protein Ubiquitination
Stem Cell Population Maintenance
Positive Regulation Of Wnt Signaling Pathway
Positive Regulation Of MRNA 3'-end Processing
Protein Destabilization
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Histone H2B Ubiquitination
Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex
Negative Regulation Of Apoptotic Process
Negative Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Fibroblast Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Cellular Response To Lipopolysaccharide
Positive Regulation Of Cell Cycle G1/S Phase Transition
Beta-catenin-TCF Complex Assembly
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Formation of RNA Pol II elongation complex
Formation of the beta-catenin:TCF transactivating complex
Hedgehog 'on' state
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
Primary hyperparathyroidism; Familial hyperparathyroidism (HRPT)
GWAS
Bipolar disorder (
21926972
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Intelligence (MTAG) (
29326435
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Chronotype (
30696823
)
Ovarian disease with few adhesions (
28333195
)
Photic sneeze reflex (
27182965
)
Subcutaneous adipose tissue (
22589738
)
Takayasu arteritis (
25604533
)
White matter hyperintensity burden (
25663218
)
Interacting Genes
81 interacting genes:
AARD
AXIN1
AXIN2
BCL6B
BIRC2
CBX8
CBY2
CCDC136
CCDC33
CCDC88B
CCHCR1
CDC73
CDK18
CDSN
CEP44
CEP57
CEP57L1
COG6
CREB5
DISC1
FAM161A
FAM161B
FBF1
GCC2-AS1
GOLGA2
HDAC4
HDX
HIF1A
HNRNPM
HOOK2
JRK
KANK2
KIAA1328
KRT6A
KRT76
LMNA
LZTS1
MAD1L1
MATR3
MBD3L1
MID2
NAB2
PAK5
PIBF1
PKN1
PLEKHA7
PPHLN1
PPP1R13B
PPP1R18
PRDM14
PRDM6
PRPF31
RBAK
RCOR3
RNF6
RTP5
SCEL
SORBS3
SYT6
TCEA2
TLE5
TP53BP2
TRIM14
TRIM29
ZBTB24
ZBTB26
ZBTB38
ZBTB39
ZNF124
ZNF2
ZNF205
ZNF23
ZNF410
ZNF417
ZNF426
ZNF438
ZNF490
ZNF544
ZNF587
ZNF599
ZNF670
35 interacting genes:
ALAS1
ANXA6
CEP70
CTNNB1
DDAH2
FAF1
FSD2
GC
GOLGA2
GOLGA6L9
H1-2
HAP1
HSF2BP
HSPA4
ITFG1
KASH5
KCNH2
KIAA1549
KIDINS220
MCM3AP
MTUS2
MYC
PICK1
PITHD1
RABEP1
RNF20
RNF40
TCEA1
TCF4
TFCP2
TOMM20
TRIM23
TSGA10
VPS37B
WWC1
Entrez ID
80705
79577
HPRD ID
06202
09581
Ensembl ID
ENSG00000135951
ENSG00000134371
Uniprot IDs
A0A218MIY9
Q9BZW7
Q6P1J9
PDB IDs
5YDE
5YDF
6TED
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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