KCNIP4 and TRH

Data Source:
BioGRID (two hybrid)

		KCNIP4	TRH
Description		potassium voltage-gated channel interacting protein 4	thyrotropin releasing hormone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex	Extracellular Region Nucleus Plasma Membrane Secretory Granule
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	Protein Binding Thyrotropin-releasing Hormone Activity
	Biological Process	Cardiac Conduction Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport	Response To Hypoxia Histamine Metabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Cold Response To Glucose Hormone-mediated Signaling Pathway Negative Regulation Of Glutamate Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Positive Regulation Of Insulin Secretion Eating Behavior Response To Ethanol Response To Corticosterone Negative Regulation Of Feeding Behavior
Pathways		Phase 1 - inactivation of fast Na+ channels	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Colorectal cancer ( 29228715) Cough in response to angiotensin-converting enzyme inhibitor drugs ( 26169577) Diverticular disease ( 30177863) Lingual gyrus volume ( 31530798) Obesity-related traits ( 23251661) Parkinson disease and lewy body pathology ( 25663231) Post bronchodilator FEV1/FVC ratio ( 26634245) Postburn scar height ( 30595539) Rheumatoid arthritis ( 21156761) Suicidal ideation ( 20877300)	Alzheimer's disease ( 30636644) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: APP ASPH COL1A2 GOLGA7 IL17A KCND2 LITAF MEOX2 PSEN1 PSEN2 TRH	5 interacting genes: ARRB2 CPE KCNIP4 LCN2 TRHR
Entrez ID		80333	7200
HPRD ID		12184	08944
Ensembl ID		ENSG00000185774	ENSG00000170893
Uniprot IDs		A8K4N3 Q6PIL6	P20396
PDB IDs
Enriched GO Terms of Interacting Partners?
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