CEP76 and CACNB3

Data Source:
BioGRID (two hybrid)

		CEP76	CACNB3
Description		centrosomal protein 76	calcium voltage-gated channel auxiliary subunit beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Protein-containing Complex	Cytosol Plasma Membrane Voltage-gated Calcium Channel Complex Membrane Apical Plasma Membrane Synapse L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Protein Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding High Voltage-gated Calcium Channel Activity Protein Kinase Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centriole Replication Ciliary Basal Body-plasma Membrane Docking	Calcium Ion Transport Chemical Synaptic Transmission Neuromuscular Junction Development T Cell Receptor Signaling Pathway Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Membrane Depolarization Calcium Ion Transport Into Cytosol Cardiac Conduction Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Cellular Response To Oxygen-glucose Deprivation Regulation Of Membrane Repolarization During Action Potential Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Membrane Hyperpolarization Negative Regulation Of Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Presynaptic depolarization and calcium channel opening Adrenaline,noradrenaline inhibits insulin secretion NCAM1 interactions Regulation of insulin secretion Regulation of insulin secretion
Drugs			Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Nimodipine Spironolactone Magnesium sulfate Levomenthol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases
GWAS
Interacting Genes		105 interacting genes: AKAP7 AKT1 ANKRD36 ASH2L BANP C22orf39 CABP5 CACNB3 CAPN3 CAVIN3 CCDC92 CCNK CDK18 CENPI CIR1 COIL CRYBA4 CSNK1G1 CUTC CWF19L2 DCTD DDX6 DEAF1 DMTN DVL3 DZIP1L EAF1 EIF1AD EP400P1 ERCC3 FAM90A1 GDAP2 GFAP GORASP2 HSF2 HSPB7 ILVBL IQUB KDM1A KDM4D KIAA1143 KIFBP KLHDC4 L3MBTL2 LATS1 LNX1 MAGEA11 MBD3 MFAP1 MISP MLH1 MYOZ1 NEK6 NFYC NHLRC2 NME5 PAICS PARD6B PATZ1 PDGFRB PDRG1 PDZD4 PDZD7 PIN1 PKP1 PLA2G6 PLCB1 POM121 RADIL RALGPS1 RBM41 RIPPLY3 RNF128 RPL9 SALL2 SCNM1 SH2D4A SINHCAF SMG9 SPG21 STK26 SUOX TBC1D27P TCEA2 TCEANC TCF19 TFAP2D THRA TOB2 TSPOAP1 TSSC4 TTC21A TTLL10 TUFT1 TXNDC9 VEZF1 WDFY3 YY1 ZBTB24 ZBTB4 ZMAT2 ZNF185 ZNF653 ZNF76 ZNF85	12 interacting genes: C20orf85 CACNA1B CACNA1C CEP76 CIAPIN1 CTBP2 FASLG GEM MEOX1 MTUS2 SKIV2L SYT1
Entrez ID		79959	784
HPRD ID		12694	11879
Ensembl ID		ENSG00000101624	ENSG00000167535
Uniprot IDs		B4DP81 Q8TAP6	P54284
PDB IDs
Enriched GO Terms of Interacting Partners?
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