RBFA and ERLIN1

Data Source:
BioGRID (two hybrid)

		RBFA	ERLIN1
Description		ribosome binding factor A	ER lipid raft associated 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrion	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding Cholesterol Binding Ubiquitin Protein Ligase Binding
	Biological Process	RRNA Processing Biological_process	Cholesterol Metabolic Process Ubiquitin-dependent ERAD Pathway SREBP Signaling Pathway Negative Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Fatty Acid Biosynthetic Process Transmembrane Transport
Pathways			ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Liver enzyme levels ( 18940312) Refractive error ( 32231278) Response to radiotherapy in cancer (late toxicity) ( 24785509) Squamous cell lung carcinoma ( 28604730) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		22 interacting genes: ABHD5 AGTRAP ANK1 CACFD1 CAV3 CMTM5 CMTM6 DERL2 ERLIN1 FATE1 FKBP7 GPR152 GPX8 HIGD1C LEPROTL1 MDK PEX12 RHEX SMIM5 SYP SYPL1 YIF1A	7 interacting genes: AGR3 BNIP2 FA2H RBFA SEC22A SEC23A TMEM199
Entrez ID		79863	10613
HPRD ID		07959	08502
Ensembl ID		ENSG00000101546	ENSG00000107566
Uniprot IDs		Q8N0V3	O75477
PDB IDs		2E7G
Enriched GO Terms of Interacting Partners?
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