FAM124B and ISCA2

Data Source:
BioGRID (two hybrid)

		FAM124B	ISCA2
Description		family with sequence similarity 124 member B	iron-sulfur cluster assembly 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding	Structural Molecule Activity Iron Ion Binding Protein Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process		Iron-sulfur Cluster Assembly Small Molecule Metabolic Process Protein Maturation By [4Fe-4S] Cluster Transfer
Pathways			Mitochondrial iron-sulfur cluster biogenesis
Drugs
Diseases
GWAS		Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Familial squamous cell lung carcinoma ( 29924316)	Advanced glycation end-product levels ( 26915486)
Interacting Genes		67 interacting genes: ABI1 ABI3 ADAMTSL4 BHLHB9 BIRC7 BLZF1 CARD9 CCDC153 CCDC85B CYSRT1 EFEMP2 EFHC2 ESM1 GIGYF1 GKAP1 GOLGA2 GPRASP2 GRB7 HSF2BP IHO1 IKZF3 ISCA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP1-5 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP9-3 LHX3 LZTS2 MBD3L1 MDFI MIPOL1 MKRN3 MTUS2 MYF5 NADK NOTCH2NLA RBPMS RINT1 RSPH3 SEPTIN14 SH2B2 SP7 SSX2IP TCF4 TLE5 TRAF2 TRIM37 TRIM42 TRIM54 TRIM8 TRIM9 TRIP6 USHBP1 USP54 WDR83 ZBED1 ZNF69 ZNF774 ZRANB1	8 interacting genes: ANKS1A EIF3E FAM124B GEM GUCD1 NTAQ1 RNF41 SUOX
Entrez ID		79843	122961
HPRD ID		08663	17090
Ensembl ID		ENSG00000124019	ENSG00000165898
Uniprot IDs		Q9H5Z6	Q86U28
PDB IDs
Enriched GO Terms of Interacting Partners?
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