ARHGEF5 and ATP13A1

Data Source:
BioGRID (two hybrid)

		ARHGEF5	ATP13A1
Description		Rho guanine nucleotide exchange factor 5	ATPase 13A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell Junction Cell Projection Cell Periphery	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding Lipid Binding	Molecular_function ATP Binding Manganese Transmembrane Transporter Activity, Phosphorylative Mechanism ATPase Activity Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of Actin Cytoskeleton Organization Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Positive Regulation Of JUN Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly Regulation Of ERK1 And ERK2 Cascade Activation Of GTPase Activity Positive Regulation Of Protein Import	Cellular Calcium Ion Homeostasis Biological_process Ion Transmembrane Transport Manganese Ion Transmembrane Transport
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Gut microbiota relative abundance (Parabacteroides) ( 33208821) Post bronchodilator FEV1/FVC ratio ( 26634245)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Toenail selenium levels ( 25343990) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: APP ATP13A1 CALCOCO2 CCNE1 CHPF COG6 EFHC2 EPM2AIP1 FKBP8 HSF2BP HSPBAP1 LMO2 LRATD1 MB21D2 MID2 NR4A1 PICK1 PLCG1 PLEKHG4 POLR1C RHOA SEPHS2 SLAIN1 TBC1D13 TCF4 TRIM27 TRIM54 ZRANB1	31 interacting genes: AGTR1 APPBP2 AQP6 ARHGEF5 BUD31 CBARP CXCR2 EBP ELOVL4 FAM209A FFAR2 GLP1R GPR42 KMT2E MANBAL MFSD14B MMD RNASEK SCN3B SLC10A6 SLC16A13 SLC30A2 SLC30A8 SLC35C2 SYPL2 TLCD4 TMBIM6 TMEM14B TMEM237 UNC93A VMA21
Entrez ID		7984	57130
HPRD ID		02932	12501
Ensembl ID		ENSG00000050327	ENSG00000105726
Uniprot IDs		Q12774	A0A024R7N2 Q9HD20
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?