LIN28A and MIR1-2

Data Source:
BioGRID (unspecified method)

		LIN28A	MIR1-2
Description		lin-28 homolog A	microRNA 1-2
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleolus Cytoplasm Rough Endoplasmic Reticulum Cytosol Polysome Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	G-quadruplex RNA Binding RNA Binding Protein Binding Zinc Ion Binding Translation Initiation Factor Binding MiRNA Binding Polysome Binding Sequence-specific MRNA Binding
	Biological Process	Germ Cell Development MiRNA Catabolic Process Negative Regulation Of Translation Stem Cell Population Maintenance Pre-miRNA Processing RNA 3'-end Processing Positive Regulation Of TOR Signaling Somatic Stem Cell Population Maintenance Positive Regulation Of Neuron Differentiation Negative Regulation Of Glial Cell Differentiation Stem Cell Differentiation Positive Regulation Of Protein Kinase B Signaling RNA 3' Uridylation Cellular Response To Glucose Stimulus Positive Regulation Of Cell Proliferation Involved In Kidney Development Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Positive Regulation Of Cytoplasmic Translation	Gene Silencing By MiRNA
Pathways		Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Glucose homeostasis traits ( 25524916) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		72 interacting genes: MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I ZDHHC17 ZNF275	78 interacting genes: ADARB1 APOBEC3B C1QBP CPSF1 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 P3H1 PATL1 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBM14 RBM4 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM71 UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		79727	406905
HPRD ID		17278
Ensembl ID		ENSG00000131914	ENSG00000284453
Uniprot IDs		Q9H9Z2
PDB IDs		2CQF 2LI8 5UDZ
Enriched GO Terms of Interacting Partners?
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