ARMC7 and SHISA6

Data Source:
BioGRID (two hybrid)

		ARMC7	SHISA6
Description		armadillo repeat containing 7	shisa family member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Postsynaptic Density AMPA Glutamate Receptor Complex Dendritic Spine Membrane Postsynaptic Membrane Asymmetric, Glutamatergic, Excitatory Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Protein Binding	Protein Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding
	Biological Process		Spermatogenesis Wnt Signaling Pathway Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Postsynaptic Neurotransmitter Receptor Activity Postsynaptic Neurotransmitter Receptor Diffusion Trapping Excitatory Chemical Synaptic Transmission Regulation Of AMPA Glutamate Receptor Clustering Regulation Of AMPA Receptor Activity
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Adventurousness ( 30643258) Copper levels ( 26025379) Daytime sleep phenotypes ( 27126917) Myopia ( 27182965) Obesity-related traits ( 23251661) Refractive error ( 23396134 32231278) Seborrheic dermatitis ( 29203360) Sleep duration (short sleep) ( 30846698) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		72 interacting genes: ABI2 ABI3 APP C11orf1 C2orf88 CBY2 CCDC28B CCDC33 CDC42EP1 CHCHD3 CPSF6 CPSF7 DISC1 DPEP2NB DTX2 EFHC2 ESS2 GATA1 GIGYF1 HGS HOXA1 IKZF1 IKZF3 INCA1 KCTD13 KRT31 KRT34 KRT39 KRT40 KRT75 KRTAP13-1 KRTAP19-7 KRTAP6-3 LZTS2 MDFI NME4 PAK5 PIMREG PLEKHG4 PNMA6A RBM48 REL RRP7A RUNDC3A SAXO1 SEPTIN14 SHISA6 SLAIN1 SPATC1L SPG21 SYF2 TASOR2 TCF4 TEX45 TFIP11 TNFAIP1 TNNI1 TRIB3 TRIM27 TRIM42 TRIM54 USP54 VIM VPS37D YPEL3 ZBTB8A ZC2HC1C ZMAT5 ZNF140 ZNF426 ZNF669 ZNF764	29 interacting genes: ANKS1A ARMC7 BAG3 CARD9 CCDC57 CDKN1A CIAO1 CTBP2 CYSRT1 EXOSC5 FBLIM1 GOLGA2 HSF2BP KAT5 KIF9 KIFC3 KRT31 KRTAP3-3 LMO3 NEDD4 OIP5 PFDN5 PLEKHG4 SMARCD1 TLE5 TRIP6 TSSK3 TTC19 UBASH3A
Entrez ID		79637	388336
HPRD ID		08649	13507
Ensembl ID		ENSG00000125449	ENSG00000188803
Uniprot IDs		J3KST7 J3KTE5 Q9H6L4	Q6ZSJ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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