HMBOX1 and GAS2L2

Data Source:
BioGRID (two hybrid)

		HMBOX1	GAS2L2
Description		homeobox containing 1	growth arrest specific 2 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Cytoplasm Actin Filament Plasma Membrane Microtubule Plus-end Ciliary Basal Body
	Molecular Function	Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding	G-protein Alpha-subunit Binding Protein Binding Microtubule Binding Cytoskeletal Anchor Activity Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Actin Crosslink Formation Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Protein Localization To Microtubule Plus-end
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
Interacting Genes		100 interacting genes: ABITRAM AEBP2 ANKRD36 APP ASB7 ATP5PO BAZ2B BEND7 BRD1 BYSL C8orf33 CARD9 CBX8 CCDC187 CCNG1 CDC7 CDCA8 CDK18 DAB1 DNTTIP1 DYNLL1 DYNLL2 ENKD1 ENTPD2 FAM13C FAM161A FAM217B FAM74A4 FAM90A1 FARS2 FGF11 FNDC11 FRMD6 FXR2 GAS2L2 GNL3L GSC2 INO80B IPO13 KAT5 KIF9 LMO1 LMO3 LNX1 MAGEH1 MCRS1 MEOX1 MEOX2 MFAP1 MORF4L1 MORF4L2 MRPL11 MRPL28 PAX5 PAX6 PIAS2 PICK1 PIP4K2B PKD1P1 POLDIP3 POLL PRKAA1 PRKAA2 PRPF18 RBMY2FP RCOR3 REEP6 RPL9 RPS25 SAP30L SCNM1 SDCBP SFR1 SH2D4A SNRPB2 SNW1 SYT6 TBP TCEA2 TCEANC TSGA10IP TUFM U2AF2 UBA6 UBE2I UBE2Z VAX1 VPS72 WT1 ZBTB24 ZBTB26 ZFYVE26 ZMAT2 ZMYM5 ZNF250 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	36 interacting genes: ABI2 BANP C7orf57 CCNDBP1 DISC1 DNAAF6 EFHC1 GOLGA2 GOLGA6L9 HMBOX1 HOOK2 HSF2BP JADE2 KCTD7 LHX3 LNX1 LRP2BP MAPRE1 MAPRE2 MAPRE3 MID2 MORN5 MTUS2 NAP1L1 PAX6 PICK1 PPP1R13B PRKAR1B RORB SAT1 SNW1 SOCS7 TFIP11 TRIM27 WWP2 ZRANB1
Entrez ID		79618	246176
HPRD ID		07964	11000
Ensembl ID		ENSG00000147421	ENSG00000270765
Uniprot IDs		D3DSU2 Q6NT76	Q8NHY3
PDB IDs		2CUF 4J19
Enriched GO Terms of Interacting Partners?
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