EPM2A and PPP1R3C

Data Source:
BioGRID (two hybrid)

		EPM2A	PPP1R3C
Description		EPM2A glucan phosphatase, laforin	protein phosphatase 1 regulatory subunit 3C
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Protein Phosphatase Type 1 Complex Cytosol
	Molecular Function	Protein Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase 1 Binding Protein Phosphatase Binding Glycogen Binding
	Biological Process	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling	Glycogen Metabolic Process Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process Protein Dephosphorylation
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora	Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases		Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 32888494 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)
Interacting Genes		16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS	9 interacting genes: APP EPM2A LONRF1 LXN NHLRC1 PPP1CA PPP1CB PPP1CC SGTA
Entrez ID		7957	5507
HPRD ID		06345	04298
Ensembl ID		ENSG00000112425	ENSG00000119938
Uniprot IDs		H0UI04 O95278	Q9UQK1
PDB IDs		4R30 4RKK
Enriched GO Terms of Interacting Partners?
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