BIRC7 and XAF1

Data Source:
BioGRID (two hybrid)

		BIRC7	XAF1
Description		baculoviral IAP repeat containing 7	XIAP associated factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol	Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Lens Development In Camera-type Eye Apoptotic Process Activation Of JUN Kinase Activity Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Regulation Of Cell Cycle Regulation Of Natural Killer Cell Apoptotic Process	Apoptotic Process Response To Interferon-beta Type I Interferon Signaling Pathway
Pathways			Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes		37 interacting genes: AURKC BOLA1 BOLA2 BOLA2B CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B GTF2A1 HTRA2 KANK2 LCOR LMO4 NTAQ1 PHF1 POLR1C PRR35 PSMB1 PTCD3 QARS1 SOX5 TEPSIN TLE5 TNPO2 TSGA10IP TTPA UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K USP2 VPS37C XAF1	18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP
Entrez ID		79444	54739
HPRD ID		05761	06978
Ensembl ID		ENSG00000101197	ENSG00000132530
Uniprot IDs		Q96CA5	Q6GPH4
PDB IDs		1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ	2LXW
Enriched GO Terms of Interacting Partners?
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