C11orf49 and ENY2

Data Source:
BioGRID (two hybrid)

		C11orf49	ENY2
Description		chromosome 11 open reading frame 49	ENY2 transcription and export complex 2 subunit
Image		No pdb structure
GO Annotations	Cellular Component		SAGA Complex Nucleoplasm Mitochondrion Nuclear Pore Nuclear Basket Transcription Export Complex 2 DUBm Complex
	Molecular Function	Protein Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity
	Biological Process		Regulation Of Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Histone Deubiquitination Poly(A)+ MRNA Export From Nucleus Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) D-dimer levels ( 21502573) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29617998) Neurociticism ( 29500382)	Metabolite levels ( 23823483) Multiple system atrophy (pathologically confirmed) ( 27629089) Night sleep phenotypes ( 27126917)
Interacting Genes		19 interacting genes: ARHGEF15 CDC16 ENY2 FH GCA GSR PHF1 PNMA5 PRKAR1A PSMA1 RAB17 RAB29 RBM48 RPL8 RPS3A TXN2 UBE3A UBQLN4 ZFHX3	6 interacting genes: APP ATXN7L3 ATXN7L3B C11orf49 HNRNPA2B1 MCM3AP
Entrez ID		79096	56943
HPRD ID		08332	13121
Ensembl ID		ENSG00000149179	ENSG00000120533
Uniprot IDs		B4DUV7 Q9H6J7	A0A024R9D9 Q9NPA8
PDB IDs			4DHX
Enriched GO Terms of Interacting Partners?
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