WDR77 and TOE1

Data Source:
BioGRID (two hybrid)

		WDR77	TOE1
Description		WD repeat domain 77	target of EGR1, exonuclease
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome Pole Plasm	Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	Protein Binding Methyl-CpG Binding Nuclear Receptor Coactivator Activity	3'-5'-exoribonuclease Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding SnRNA Binding Metal Ion Binding
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Pole Plasm Assembly Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription, DNA-templated Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development	SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS
Interacting Genes		44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZMYND19 ZNF207	25 interacting genes: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83
Entrez ID		79084	114034
HPRD ID		14387	18212
Ensembl ID		ENSG00000116455	ENSG00000132773
Uniprot IDs		A0A024R0H7 Q9BQA1	Q96GM8
PDB IDs		4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S 6RLL 6RLQ 6UXX 6UXY 6V0N 6V0O	2FC6
Enriched GO Terms of Interacting Partners?
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