KCTD15 and TFAP2A

KCTD15

TFAP2A

Description potassium channel tetramerization domain containing 15 transcription factor AP-2 alpha
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • Body mass index ( 19079260 19079261 28892062 25673413 20935630 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Body mass index in physically active individuals ( 28448500)
  • Dental caries (decayed and filled deciduous teeth) ( 31533690)
  • Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Major depressive disorder ( 23377640)
  • Obesity-related traits ( 23251661)
  • Response to antidepressants (symptom remission) ( 29160301)
  • Response to SSRI (symptom remission) ( 29160301)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Weight ( 19079260)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Breast cancer in BRCA2 mutation carriers ( 23544012)
  • Glucose homeostasis traits ( 25524916)
  • Iron status biomarkers (ferritin levels) ( 28334935)
  • Metabolite levels ( 23823483)
  • Ovarian cancer ( 30557369)
  • Refractive error ( 32231278)
  • Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
  • Zinc levels ( 26025379)
Interacting Genes 14 interacting genes: ATXN1 CYSRT1 ENSA KCTD1 NBPF19 NOTCH2NLA NOXA1 NTAQ1 REN TFAP2A TRIM27 TRIM55 TRIM63 WIPI1 38 interacting genes: APC CASP1 CASP3 CASP6 CITED2 CITED4 CLTC CSNK2A1 CSNK2B CTNNB1 DEK EP300 EPN1 EPN2 EPS15 GSTO2 HIP1 INCA1 KCTD15 LDLRAP1 MAGI1 MKRN3 MYC NFKB1 NPM1 PPARG PRKAA2 PRKD1 RB1 SRA1 SUMO4 SYT1 TP53 UBE2I VEGFA WWP1 WWP2 YBX1
Entrez ID 79047 7020
HPRD ID 13765 00128
Ensembl ID ENSG00000153885 ENSG00000137203
Uniprot IDs Q96SI1 P05549
PDB IDs
Enriched GO Terms of Interacting Partners?
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