ZFYVE21 and YIF1A

Data Source:
BioGRID (two hybrid)

		ZFYVE21	YIF1A
Description		zinc finger FYVE-type containing 21	Yip1 interacting factor homolog A, membrane trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Focal Adhesion	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process		Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport IRE1-mediated Unfolded Protein Response
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 26426971) Hemoglobin ( 32888494) Schizophrenia ( 25056061 29483656)	Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		26 interacting genes: AGTRAP ARL6IP1 CAPN2 CMTM4 FBXO7 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP5-9 MID2 MTUS2 NOTCH2NLA PDE4DIP PTK2 RABAC1 REEP6 RTN4 SIAH1 SMIM5 TRAF1 TRIM27 TUBB YIF1A	72 interacting genes: APOA5 AQP6 BNIP2 C4orf3 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 HSD17B11 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35C2 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27
Entrez ID		79038	10897
HPRD ID		15733	06755
Ensembl ID		ENSG00000100711	ENSG00000174851
Uniprot IDs		Q9BQ24	A6NGW1 A8K509 O95070
PDB IDs		2RRF
Enriched GO Terms of Interacting Partners?
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