RAB7A and RAB13

Data Source:
BioGRID (pull down)

		RAB7A	RAB13
Description		RAB7A, member RAS oncogene family	RAB13, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Lysosome Lysosomal Membrane Late Endosome Lipid Droplet Cytosol Plasma Membrane Endosome Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Retromer Complex Late Endosome Membrane Extrinsic Component Of Lysosome Membrane Melanosome Membrane Phagocytic Vesicle Extracellular Exosome	Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Bicellular Tight Junction Synaptic Vesicle Lateral Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Neuron Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Retromer Complex Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Autophagosome Assembly Protein Targeting To Lysosome Endocytosis Epidermal Growth Factor Catabolic Process Endosome To Lysosome Transport Protein Transport Lipid Catabolic Process Viral Release From Host Cell Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Protein To Membrane Docking Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Positive Regulation Of Viral Process Lipophagy Phagosome Maturation Phagosome Acidification Phagosome-lysosome Fusion Endosome To Plasma Membrane Protein Transport Multi-organism Intercellular Transport Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Negative Regulation Of Intralumenal Vesicle Formation	Vesicle Docking Involved In Exocytosis Protein Secretion Protein Kinase A Signaling Endosomal Transport Regulation Of Exocytosis Cortical Actin Cytoskeleton Organization Neuron Projection Development Endocytic Recycling Cellular Response To Insulin Stimulus Endothelial Cell Chemotaxis Post-translational Protein Modification Trans-Golgi Network To Recycling Endosome Transport Golgi Vesicle Fusion To Target Membrane Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Sertoli Cell Barrier
Pathways		MHC class II antigen presentation Neutrophil degranulation TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Prevention of phagosomal-lysosomal fusion Suppression of autophagy	Translocation of SLC2A4 (GLUT4) to the plasma membrane RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs		Guanosine-5'-Diphosphate
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Body fat mass ( 28552196) Facial morphology traits (63 three-dimensional facial segments) ( 29459680)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		27 interacting genes: CHM KRTAP10-3 KRTAP10-9 PPP2R1A PPP2R1B PRKN RAB13 RAB17 RAB22A RAB4A RAB4B RAB6A RABAC1 RABGGTB RILP RNF115 SLC2A4 SNX3 TP53 UCHL5 VPS11 VPS16 VPS18 VPS26A VPS29 VPS39 VPS41	10 interacting genes: APP MICALL1 PDE6D RAB11A RAB7A RAB8A RABGAP1L SMAD4 SMURF2 TGFBR1
Entrez ID		7879	5872
HPRD ID		03805	04053
Ensembl ID		ENSG00000075785	ENSG00000143545
Uniprot IDs		A0A158RFU6 P51149	A0A087WWB9 P51153 Q504R6
PDB IDs		1T91 1YHN 3LAW 6IYB 6WCW
Enriched GO Terms of Interacting Partners?
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