SEMA3B and SEMA3A

Data Source:
HPRD (in vivo)

		SEMA3B	SEMA3A
Description		semaphorin 3B	semaphorin 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Integral Component Of Plasma Membrane Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Space Integral Component Of Plasma Membrane Axon Dendrite
	Molecular Function	Semaphorin Receptor Binding Chemorepellent Activity	Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Neural Crest Cell Migration Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Migration Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Chemorepulsion Of Axon Semaphorin-plexin Signaling Pathway	Neural Crest Cell Migration Neuron Migration Regulation Of Heart Rate Apoptotic Process Axon Guidance Axonal Fasciculation Motor Neuron Axon Guidance Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Neuron Projection Development Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Nerve Development Olfactory Bulb Development Branchiomotor Neuron Axon Guidance Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Positive Regulation Of Cell Migration Ventral Trunk Neural Crest Cell Migration Positive Regulation Of JNK Cascade Sympathetic Nervous System Development Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Axon Extension Involved In Axon Guidance Axon Extension Involved In Axon Guidance Sensory System Development Negative Chemotaxis Axonogenesis Involved In Innervation Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Sympathetic Ganglion Development Trigeminal Ganglion Development Semaphorin-plexin Signaling Pathway Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Basal Dendrite Arborization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neural Crest Cell Migration Involved In Sympathetic Nervous System Development Facioacoustic Ganglion Development Positive Regulation Of Male Gonad Development Positive Regulation Of Neuron Migration
Pathways			Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Obese vs. thin ( 30677029) Sleep duration (short sleep) ( 30846698)	Attention deficit hyperactivity disorder ( 21784300) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Iris characteristics ( 21835309) Major depression and alcohol dependence ( 29071344) Nose morphology ( 29921221) Obesity-related traits ( 23251661) PR interval ( 32439900) Prion diseases ( 22210626) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist circumference ( 28552196)
Interacting Genes		22 interacting genes: BOLL CARD10 CYSRT1 HSF2BP KPRP KRTAP1-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP19-5 KRTAP5-9 MDFI NAA10 NBPF19 NOTCH2NLA NRP1 NRP2 PAK6 PICK1 RBPMS2 SEMA3A TRIP13	2 interacting genes: NRP1 SEMA3B
Entrez ID		7869	10371
HPRD ID		03179	04908
Ensembl ID		ENSG00000012171	ENSG00000075213
Uniprot IDs		A0A0C4DGV8 B4DEK9 Q13214 Q6PI51	Q14563
PDB IDs
Enriched GO Terms of Interacting Partners?
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