IFRD2 and OAS3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IFRD2	OAS3
Description		interferon related developmental regulator 2	2'-5'-oligoadenylate synthetase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process		Nucleobase-containing Compound Metabolic Process Response To Virus Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Regulation Of Ribonuclease Activity
Pathways			Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Body mass index ( 26426971) Chronic lymphocytic leukemia ( 28165464) HDL cholesterol ( 21909109) High density lipoprotein cholesterol levels ( 30718733) Low HDL-cholesterol levels ( 31006500) Myocardial infarction ( 30226566) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239)
Interacting Genes		6 interacting genes: APP JRK MDFI NEDD4L OAS3 POT1	5 interacting genes: DHX30 EIF6 FTSJ3 IFRD2 MAVS
Entrez ID		7866	4940
HPRD ID		04101	04519
Ensembl ID		ENSG00000214706	ENSG00000111331
Uniprot IDs		Q12894	Q9Y6K5
PDB IDs			4S3N
Enriched GO Terms of Interacting Partners?
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