ZNF174 and ZKSCAN8

Data Source:
BioGRID (two hybrid)

		ZNF174	ZKSCAN8
Description		zinc finger protein 174	zinc finger with KRAB and SCAN domains 8
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane Actin Cytoskeleton	Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Mean corpuscular volume ( 27863252) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		9 interacting genes: CDK6 MZF1 SCAND1 ZKSCAN8 ZNF20 ZNF24 ZSCAN18 ZSCAN22 ZSCAN32	10 interacting genes: APP FBXO7 MAGOH PRNP TCEA2 ZNF165 ZNF174 ZNF24 ZNF444 ZNF587
Entrez ID		7727	7745
HPRD ID		04876	03760
Ensembl ID		ENSG00000103343	ENSG00000198315
Uniprot IDs		I3L2H2 Q15697	A0A024RCK7 Q15776 Q59HG5
PDB IDs		1Y7Q
Enriched GO Terms of Interacting Partners?
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