ZNF157 and KDM6A

		ZNF157	KDM6A
Description		zinc finger protein 157	lysine demethylase 6A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Histone Methyltransferase Complex MLL3/4 Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Chromatin DNA Binding Metal Ion Binding Dioxygenase Activity Histone Demethylase Activity (H3-K27 Specific)
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Chromatin Remodeling Heart Development Regulation Of Gene Expression Histone H3-K4 Methylation Histone H3-K27 Demethylation
Pathways		Generic Transcription Pathway	HDMs demethylate histones Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Optic nerve measurement (disc area) ( 20395239)
Interacting Genes			11 interacting genes: GSC2 H3-4 H3C1 H3C14 MEOX2 MTDH NKX2-5 SMAD9 SRF TBX5 TLE1
Entrez ID		7712	7403
HPRD ID		02064	02131
Ensembl ID		ENSG00000147117	ENSG00000147050
Uniprot IDs		P51786	A0A087X0R0 A0A6Q8PFK0 B4E0L8 B7ZKN1 B7ZKN5 B7ZKN6 E1U0S6 F5H5V6 F5H6S1 F8W8R6 O15550 Q59HG3 Q86TD1
PDB IDs			3AVR 3AVS 6FUK 6FUL
Enriched GO Terms of Interacting Partners?
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