ZBTB14 and RNASEH2B

Data Source:
BioGRID (two hybrid)

		ZBTB14	RNASEH2B
Description		zinc finger and BTB domain containing 14	ribonuclease H2 subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome	Nucleoplasm Ribonuclease H2 Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development	RNA Catabolic Process Ribonucleotide Metabolic Process
Pathways
Drugs
Diseases			Aicardi-Goutieres Syndrome (AGS)
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872)	Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Metabolite levels ( 23823483) Rheumatoid arthritis (ACPA-negative) ( 24532677) Systolic blood pressure ( 30224653)
Interacting Genes		50 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2	2 interacting genes: WT1 ZBTB14
Entrez ID		7541	79621
HPRD ID		03674	07757
Ensembl ID		ENSG00000198081	ENSG00000136104
Uniprot IDs		B2R850 O43829	A0A2R8Y883 Q5TBB1 Q8N451
PDB IDs			3P56 3P87 3PUF
Enriched GO Terms of Interacting Partners?
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