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XRCC3 and ZSWIM7
Data Source:
BioGRID
(pull down)
XRCC3
ZSWIM7
Description
X-ray repair cross complementing 3
zinc finger SWIM-type containing 7
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Mitochondrion
Cytosol
Rad51C-XRCC3 Complex
Perinuclear Region Of Cytoplasm
Nucleus
Shu Complex
Molecular Function
Four-way Junction DNA Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Crossover Junction Endodeoxyribonuclease Activity
Protein Binding
Zinc Ion Binding
Biological Process
Telomere Maintenance Via Recombination
Double-strand Break Repair Via Homologous Recombination
DNA Repair
DNA Recombination
Cellular Response To DNA Damage Stimulus
Response To Organic Substance
Regulation Of Centrosome Duplication
Interstrand Cross-link Repair
Double-strand Break Repair Via Synthesis-dependent Strand Annealing
Resolution Of Mitotic Recombination Intermediates
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
T-circle Formation
Telomeric Loop Disassembly
Telomere Maintenance Via Telomere Trimming
Double-strand Break Repair Via Homologous Recombination
Protein Stabilization
Pathways
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
31043756
)
Body mass index (
26426971
29273807
)
Schizophrenia (
25056061
29483656
)
Blood pressure (smoking interaction) (
25189868
)
Interacting Genes
22 interacting genes:
BAP1
BCAS3
CXCL1
FANCG
GREB1
ITIH5
LRATD2
MRC2
OSGIN1
PALB2
PSMC3IP
RAD51
RAD51C
RAD51D
RNF20
SCGB3A1
SERPINB5
SNAI1
SWSAP1
TFF1
ZNHIT3
ZSWIM7
4 interacting genes:
RAD51D
SWSAP1
UQCRB
XRCC3
Entrez ID
7517
125150
HPRD ID
07201
19095
Ensembl ID
ENSG00000126215
ENSG00000214941
Uniprot IDs
O43542
Q53XC8
A0A024RD64
Q19AV6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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