XK and KEL

Data Source:
HPRD (in vivo)

		XK	KEL
Description		X-linked Kx blood group	Kell metallo-endopeptidase (Kell blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transporter Activity Protein Binding	Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Amino Acid Transport	Cellular Calcium Ion Homeostasis Regulation Of Cell Size Cellular Magnesium Ion Homeostasis Protein Processing Regulation Of Axon Diameter Vasoconstriction Myelination Skeletal Muscle Fiber Development Negative Regulation Of Potassium Ion Transmembrane Transport
Pathways		Peptide ligand-binding receptors	Peptide ligand-binding receptors
Drugs			Phosphoramidon
Diseases		Core neuroacanthocytosis syndromes, including: Chorea-acanthocytosis (ChAc); McLeod syndrome (MLS); Huntington's disease-like 2 (HDL2); Pantothenate kinase associated neurodegeneration (PKAN) McLeod syndrome
GWAS			Alcoholic chronic pancreatitis ( 28754779) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252)
Interacting Genes		4 interacting genes: CLGN CSNK2A1 KEL PRKCA	12 interacting genes: ADIPOQ C3orf52 C5 CLDN19 EDN1 EDN2 EDN3 EWSR1 PM20D2 TUBA1A UBC XK
Entrez ID		7504	3792
HPRD ID		02444	00194
Ensembl ID		ENSG00000047597	ENSG00000197993
Uniprot IDs		P51811	A0A077QP03 P23276
PDB IDs
Enriched GO Terms of Interacting Partners?
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