WNT7A and STRN4

Data Source:
HPRD (two hybrid)

		WNT7A	STRN4
Description		Wnt family member 7A	striatin 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface Endocytic Vesicle Membrane Extracellular Matrix Extracellular Exosome Schaffer Collateral - CA1 Synapse Presynapse Glutamatergic Synapse	Cytoplasm Membrane Dendrite Dendritic Spine FAR/SIN/STRIPAK Complex
	Molecular Function	Signaling Receptor Binding Frizzled Binding Cytokine Activity Protein Binding Receptor Ligand Activity	Protein Binding Calmodulin Binding Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Embryonic Axis Specification Cartilage Condensation Angiogenesis Chondrocyte Differentiation Neurotransmitter Secretion Axonogenesis Sex Differentiation Dorsal/ventral Pattern Formation Positive Regulation Of Endothelial Cell Migration Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Wnt Signaling Pathway Cerebellar Granule Cell Differentiation Cell Proliferation In Forebrain Central Nervous System Vasculogenesis Establishment Of Cell Polarity Neuron Differentiation Regulation Of Axon Diameter Positive Regulation Of Cellular Protein Metabolic Process Response To Estradiol Somatic Stem Cell Population Maintenance Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Wound Healing, Spreading Of Epidermal Cells Synaptic Vesicle Recycling Embryonic Digit Morphogenesis Negative Regulation Of Apoptotic Process Response To Estrogen Cell Fate Commitment Asymmetric Protein Localization Involved In Cell Fate Determination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of JNK Cascade Somatic Stem Cell Division Stem Cell Development Negative Regulation Of Neurogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Oviduct Development Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Dendritic Spine Morphogenesis Uterus Morphogenesis Secondary Palate Development Lens Fiber Cell Development Cellular Response To Transforming Growth Factor Beta Stimulus Presynapse Assembly Postsynapse Assembly Regulation Of Postsynapse Organization Excitatory Synapse Assembly Positive Regulation Of Excitatory Synapse Assembly Positive Regulation Of Protein Localization To Presynapse Regulation Of Presynapse Assembly Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Biological_process
Pathways		WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases		Fuhrmann syndrome; Fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly Al-Awadi/Raas-Rothschild syndrome; Ulna and fibula, absence of, with sever limb deficiency
GWAS		Body mass index ( 26426971) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Creatinine levels ( 29124443) Estimated glomerular filtration rate ( 31152163 29124443) Glomerular filtration rate (creatinine) ( 26831199) Hematocrit ( 32888494) Pulse pressure ( 27841878 30578418) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Serum uric acid levels ( 29124443)	Chronic lymphocytic leukemia ( 18758461 28165464) Primary sclerosing cholangitis ( 23603763)
Interacting Genes		3 interacting genes: FZD5 FZD9 STRN4	23 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 WIPI2 WNT7A
Entrez ID		7476	29888
HPRD ID		03341	18125
Ensembl ID		ENSG00000154764	ENSG00000090372
Uniprot IDs		O00755	B3KPF6 Q59GV6 Q9NRL3
PDB IDs		4UZQ
Enriched GO Terms of Interacting Partners?
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