CLRN1 and CLDN19

Data Source:
BioGRID (two hybrid)

		CLRN1	CLDN19
Description		clarin 1	claudin 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Microvillus Microtubule Cytoskeleton Integral Component Of Membrane Lamellipodium Trans-Golgi Network Transport Vesicle Stereocilium Basal Part Of Cell	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Structural Molecule Activity Identical Protein Binding
	Biological Process	Actin Filament Organization Visual Perception Sensory Perception Of Sound Positive Regulation Of Lamellipodium Assembly Photoreceptor Cell Maintenance Cell Motility Response To Stimulus Sensory Perception Of Light Stimulus Equilibrioception Auditory Receptor Cell Stereocilium Organization	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases		Usher syndrome (US)
GWAS		Chronotype ( 30696823) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)
Interacting Genes		28 interacting genes: ALG8 BRICD5 C2CD2L CANT1 CCL4L2 CLDN19 CTXN3 DRAM1 FAM24B FUT9 ITGAM MFSD5 MGST3 NRM SEC22B SLC34A3 TMEM140 TMEM147 TMEM222 TMEM239 TMEM31 TMEM50B TMEM86B TMIE TMPPE TMPRSS4 UNC50 ZDHHC15	63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14
Entrez ID		7401	149461
HPRD ID		05905	10834
Ensembl ID		ENSG00000163646	ENSG00000164007
Uniprot IDs		P58418	Q8N6F1
PDB IDs
Enriched GO Terms of Interacting Partners?
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