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UBE2A and ZMYM2
Data Source:
HPRD
(in vitro, two hybrid, in vivo)
UBE2A
ZMYM2
Description
ubiquitin conjugating enzyme E2 A
zinc finger MYM-type containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
XY Body
Nucleoplasm
Cytosol
HULC Complex
Cytosol
PML Body
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Conjugating Enzyme Binding
Biological Process
Protein Polyubiquitination
Blastocyst Hatching
DNA Repair
Postreplication Repair
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cell Population Proliferation
Response To UV
Protein Ubiquitination
Histone Ubiquitination
Histone H2A Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Maternal Process Involved In Female Pregnancy
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Biological_process
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease
Signaling by FLT3 fusion proteins
Signaling by FLT3 fusion proteins
Drugs
Diseases
GWAS
Brain connectivity (
23471985
)
Adult body size (
32376654
)
Facial emotion recognition (happy faces) (
28608620
)
Hand grip strength (
29691431
)
Interacting Genes
26 interacting genes:
CBX5
CDK1
CDK2
CDK9
CDKN2A
CRMP1
EEF1D
H2BC21
HLTF
KCMF1
MDM2
PCNA
PRKN
RAD18
RC3H1
RNF20
RNF4
RNF40
SDCBP
TP53
TRIM27
UBA1
UBR1
UBR3
UBR5
ZMYM2
26 interacting genes:
CEBPE
CREB1
CREBBP
FBXL17
FUS
GMCL1
HNRNPA2B1
HNRNPH3
IKZF3
PAICS
PTBP1
RCOR1
SFPQ
SKIL
SMAD3
SMAD4
SNIP1
SREBF2
SUMO1
SUMO2
TSC22D2
UBE2A
UBE2I
UBTF
ZBTB3
ZNF512B
Entrez ID
7319
7750
HPRD ID
02422
03745
Ensembl ID
ENSG00000077721
ENSG00000121741
Uniprot IDs
A0A0D9SG71
P49459
A0A024RDS3
A8K126
Q9UBW7
PDB IDs
6CYO
6CYR
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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