UBC and GRB2

Data Source:
BioGRID (two hybrid)

		UBC	GRB2
Description		ubiquitin C	growth factor receptor bound protein 2
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Endocytic Vesicle Membrane Vesicle Host Cell Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Cell-cell Junction COP9 Signalosome Vesicle Membrane Extracellular Exosome Grb2-EGFR Complex
	Molecular Function	Protease Binding RNA Binding Protein Binding Protein Tag Ubiquitin Protein Ligase Binding	Phosphotyrosine Residue Binding RNA Binding Epidermal Growth Factor Receptor Binding Neurotrophin TRKA Receptor Binding Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Insulin Receptor Substrate Binding Protein-containing Complex Binding Ephrin Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Activation Of MAPK Activity Protein Polyubiquitination Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Protein Targeting To Peroxisome Transforming Growth Factor Beta Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling JNK Cascade Wnt Signaling Pathway Endosomal Transport Protein Ubiquitination Protein Deubiquitination Viral Life Cycle Virion Assembly Cytokine-mediated Signaling Pathway Modification-dependent Protein Catabolic Process Translesion Synthesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Anaphase-promoting Complex-dependent Catabolic Process Nucleotide-excision Repair, DNA Incision TRIF-dependent Toll-like Receptor Signaling Pathway Interstrand Cross-link Repair Error-prone Translesion Synthesis DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of MRNA Stability Cellular Protein Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Stress-activated MAPK Cascade Transmembrane Transport Membrane Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Interleukin-1-mediated Signaling Pathway Global Genome Nucleotide-excision Repair Error-free Translesion Synthesis Intracellular Transport Of Virus	MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway Ras Protein Signal Transduction Axon Guidance Aging Insulin Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Viral Process Cytokine-mediated Signaling Pathway Positive Regulation Of Actin Filament Polymerization T Cell Costimulation Actin Cytoskeleton Reorganization Receptor Internalization Entry Of Bacterium Into Host Cell Interleukin-15-mediated Signaling Pathway Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ERBB2 Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Signal Transduction In Response To DNA Damage Regulation Of MAPK Cascade Positive Regulation Of Ras Protein Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Anatomical Structure Formation Involved In Morphogenesis Leukocyte Migration Positive Regulation Of Protein Kinase B Signaling Branching Involved In Labyrinthine Layer Morphogenesis Membrane Organization Cellular Response To Ionizing Radiation Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Activation of NF-kappaB in B cells ISG15 antiviral mechanism Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants ER-Phagosome pathway Downregulation of ERBB4 signaling Spry regulation of FGF signaling Downregulation of ERBB2:ERBB3 signaling Budding and maturation of HIV virion NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment DDX58/IFIH1-mediated induction of interferon-alpha/beta APC/C:Cdc20 mediated degradation of Cyclin B Autodegradation of Cdh1 by Cdh1:APC/C SCF-beta-TrCP mediated degradation of Emi1 APC/C:Cdc20 mediated degradation of Securin APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Cdc20:Phospho-APC/C mediated degradation of Cyclin A Membrane binding and targetting of GAG proteins Assembly Of The HIV Virion APC-Cdc20 mediated degradation of Nek2A Vpu mediated degradation of CD4 Vif-mediated degradation of APOBEC3G EGFR downregulation SCF(Skp2)-mediated degradation of p27/p21 Degradation of beta-catenin by the destruction complex TCF dependent signaling in response to WNT Downstream TCR signaling NRIF signals cell death from the nucleus p75NTR recruits signalling complexes NF-kB is activated and signals survival Regulation of activated PAK-2p34 by proteasome mediated degradation NOTCH1 Intracellular Domain Regulates Transcription Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Downregulation of SMAD2/3:SMAD4 transcriptional activity Downregulation of SMAD2/3:SMAD4 transcriptional activity SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Separation of Sister Chromatids Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Regulation of PLK1 Activity at G2/M Transition Constitutive Signaling by NOTCH1 PEST Domain Mutants Stimuli-sensing channels Constitutive Signaling by NOTCH1 HD Domain Mutants FCERI mediated NF-kB activation Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus Regulation of innate immune responses to cytosolic DNA Glycogen synthesis Autodegradation of the E3 ubiquitin ligase COP1 Deactivation of the beta-catenin transactivating complex Myoclonic epilepsy of Lafora ABC-family proteins mediated transport Circadian Clock TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 AUF1 (hnRNP D0) binds and destabilizes mRNA Asymmetric localization of PCP proteins Degradation of AXIN Degradation of DVL Regulation of FZD by ubiquitination PINK1-PRKN Mediated Mitophagy N-glycan trimming in the ER and Calnexin/Calreticulin cycle Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Dectin-1 mediated noncanonical NF-kB signaling CLEC7A (Dectin-1) signaling Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'on' state Hedgehog 'on' state Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Negative regulation of FGFR3 signaling Negative regulation of FGFR4 signaling Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis Regulation of RAS by GAPs TNFR2 non-canonical NF-kB pathway Negative regulation of MAPK pathway Regulation of necroptotic cell death NIK-->noncanonical NF-kB signaling Defective CFTR causes cystic fibrosis MAP3K8 (TPL2)-dependent MAPK1/3 activation HDR through Homologous Recombination (HRR) MAPK6/MAPK4 signaling UCH proteinases UCH proteinases Josephin domain DUBs Ub-specific processing proteases Ovarian tumor domain proteases Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Processing of DNA double-strand break ends DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation Regulation of TP53 Degradation Regulation of TP53 Activity through Methylation Negative regulation of MET activity CDT1 association with the CDC6:ORC:origin complex Orc1 removal from chromatin CDK-mediated phosphorylation and removal of Cdc6 Cyclin D associated events in G1 G2/M Checkpoints Stabilization of p53 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Ubiquitin-dependent degradation of Cyclin D PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 The role of GTSE1 in G2/M progression after G2 checkpoint FBXL7 down-regulates AURKA during mitotic entry and in early mitosis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Downregulation of ERBB2 signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes Synthesis of active ubiquitin: roles of E1 and E2 enzymes E3 ubiquitin ligases ubiquitinate target proteins InlB-mediated entry of Listeria monocytogenes into host cell InlB-mediated entry of Listeria monocytogenes into host cell InlA-mediated entry of Listeria monocytogenes into host cells RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity Regulation of RUNX3 expression and activity Regulation of PTEN localization Regulation of PTEN stability and activity Neddylation ER Quality Control Compartment (ERQC) Regulation of expression of SLITs and ROBOs Regulation of expression of SLITs and ROBOs NOTCH3 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus TICAM1-dependent activation of IRF3/IRF7 TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling Peroxisomal protein import Peroxisomal protein import Regulation of signaling by CBL Endosomal Sorting Complex Required For Transport (ESCRT) Iron uptake and transport Negative regulators of DDX58/IFIH1 signaling Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Negative regulation of NOTCH4 signaling Chaperone Mediated Autophagy Late endosomal microautophagy Prevention of phagosomal-lysosomal fusion Modulation by Mtb of host immune system Alpha-protein kinase 1 signaling pathway Aggrephagy Aggrephagy RAS processing Pexophagy Maturation of protein E Maturation of protein E Negative regulation of FLT3 FLT3 signaling by CBL mutants TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Amyloid fiber formation Antigen processing: Ubiquitination & Proteasome degradation	Interleukin-15 signaling Interleukin-15 signaling STAT5 activation downstream of FLT3 ITD mutants Signaling by FLT3 ITD and TKD mutants Signaling by FLT3 ITD and TKD mutants
Drugs		N-Formylmethionine	Pegademase 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
Diseases
GWAS		HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29403010) Total cholesterol levels ( 29403010)	Deep white matter hyperintensities ( 32517579) Multiple sclerosis ( 31604244) Systemic lupus erythematosus ( 29848360 26502338 28714469) Systemic sclerosis ( 31672989) Triglyceride levels ( 32203549)
Interacting Genes		647 interacting genes: ABCB7 ABL1 ABRAXAS1 ABRAXAS2 ACTA1 ACTC1 ACTL8 ADH7 ADRM1 AGO2 AGRN AGTPBP1 ALG1 AMFR AMPH ANAPC1 ANAPC11 ANAPC2 ANAPC7 ANGPTL3 ANKIB1 ANKRD13A ANKRD13B ANKRD13D ANKRD30A ANKS1A ANKS1B ANP32E ANTXR1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 AREL1 ARIH1 ARIH2 ARMC1 ARRB2 ASB11 ASB2 ASCC2 ASCC3 ASXL1 ASXL2 ATP5PD ATXN3 ATXN3L ATXN7L3 AUP1 BABAM1 BABAM2 BAP1 BARD1 BARX1 BCAS2 BCR BECN1 BFAR BIN1 BIRC2 BIRC3 BRAP BRCA1 BRCC3 BRF1 BSG BTD BTRC C8orf34 CAPN15 CASP8 CAVIN1 CAVIN3 CBL CBLB CBLC CBR1 CBR3 CCDC50 CCDC92 CD2 CD2AP CDC20 CDC42 CDC45 CDH2 CDH22 CDIP1 CDK17 CDY1B CENPE CEP164 CEP192 CEP55 CEP83 CFAP36 CHD3 CHGA CHP1 CHUK CLN8 CLU COL1A1 COPB1 CPT1A CRACD CTBP2 CTRC CUEDC1 CUEDC2 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYLD DAXX DAZAP2 DCUN1D1 DDI1 DDI2 DDX19B DDX58 DECR2 DENR DESI1 DHX15 DLGAP4 DMBX1 DNAH7 DNAJB2 DNASE2B DOCK6 DPH1 DPY30 ECE2 EFS EIF3A ELL ELOVL5 EP300 EPN1 EPN2 EPN3 EPS15 EPS15L1 ERCC6 ERGIC2 ERVK13-1 EXOSC8 FAAP20 FAF1 FAM168A FAN1 FAT1 FBH1 FBXL15 FBXO44 FCHO2 FETUB FGA FIS1 FLOT1 FLOT2 FSHR GARNL3 GBF1 GFPT2 GFUS GGA1 GGA3 GLG1 GRB2 GTF2H1 GTF2I GTF2IRD1 H2AC18 H2AC20 H2BC21 HACD1 HACD2 HDAC5 HDAC6 HECW1 HERC1 HERC2 HERC3 HERC4 HGS HLTF HMGN2 HNRNPM HPDL HRNR HSD17B11 HSPA8 HSPG2 HUWE1 HYDIN HYDIN2 IDE IGF1R IKBKB IKBKG ILF3 ING1 INPPL1 IRS1 ISX ITCH ITGAV ITSN2 JOSD1 JOSD2 JUN KCTD7 KDM3B KEAP1 KEL KHDRBS1 KIAA0586 KLHL11 KLHL13 KLHL7 LACTB LAMA1 LAMA5 LAMB1 LAMC1 LAPTM5 LARP1B LIMA1 LINC02593 LNPK LTF LTN1 MACF1 MAD1L1 MALT1 MAP2K4 MAP3K7 MAP4 MAPRE2 MARCHF6 MARCHF7 MBOAT7 MDM2 MDM4 MDN1 MED15 MINDY1 MINDY2 MINDY3 MINDY4 MORC3 MRPL37 MTERF4 MTURN MUC16 MUC5B MUL1 MVP MYCBP MYL1 MYL3 MYO6 NAA10 NAT10 NBPF1 NBPF10 NBPF11 NBPF12 NBPF14 NBPF8 NBPF9 NBR1 NCK2 NCKAP5L NCOA6 NDC1 NDUFB9 NDUFS8 NEDD4 NEDD4L NEK8 NEURL3 NFIA NFX1 NPLOC4 NPM1 NPTN NSFL1C NSMCE1 NT5C1B NXPH4 OGT OPA3 OPRM1 OPTN OR7G3 OSBPL8 OTOG OTUB1 OTUB2 OTUD1 OTUD3 OTUD4 OTUD5 OTUD6A OTUD6B OTUD7A OTUD7B P4HTM PABPC4 PARP10 PCBP2 PCMTD1 PDCD6IP PDE12 PDS5A PEDS1 PELI1 PHF20L1 PHPT1 PIK3C2B PLAA PLEC PLEKHB2 PLSCR4 PMS2 POLH POLI POLR2C POP5 PPA1 PPARG PPARGC1A PPL PPM1D PRAME PRDX4 PRKCI PRKN PRPF8 PRR23B PSMA6 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PTH1R PTOV1 PTPN2 PTPN23 PUS7L R3HDM4 RABEP1 RABEP2 RABGEF1 RAC1 RAD18 RAD23A RAD23B RAG1 RASAL2 RB1CC1 RBCK1 RC3H2 RCHY1 RECQL REV1 RFC1 RGPD3 RGS2 RIOK3 RNF11 RNF111 RNF114 RNF115 RNF123 RNF125 RNF126 RNF130 RNF144A RNF144B RNF145 RNF151 RNF165 RNF168 RNF169 RNF181 RNF182 RNF2 RNF216 RNF31 RNF38 RNF4 RNF5 RNF8 RPL12 RPL7L1 RPN1 RPS3 RTL8B RTL8C RTTN RYBP SBF2 SCD SDC4 SDCBP SDF2 SDK1 SEMA3F SEPTIN1 SEPTIN7P2 SFPQ SGK1 SGPP1 SH3KBP1 SHARPIN SLC27A2 SLC38A5 SLC5A6 SLIT2 SLX4 SMAD1 SMURF1 SMURF2 SMYD4 SNCA SNRNP25 SNRPA SNTB2 SNTG1 SOCS5 SPAG1 SPECC1L SPRTN SQSTM1 SRPRB STAM STAM2 STAMBP STUB1 SUN5 SYNE2 TAB1 TAB2 TAC3 TAPBP TAX1BP1 TBC1D15 TBC1D5 TBXAS1 TCAF1 TCEAL1 TCHH TCOF1 TCP10L3 TDRD3 THG1L TIAM1 TMEM120A TMEM132A TMEM160 TMEM201 TMEM223 TNFAIP3 TNFAIP6 TNIP1 TNIP2 TNIP3 TNRC6A TNRC6C TOLLIP TOM1 TOM1L1 TOM1L2 TOPORS TOR1AIP2 TRAF2 TRAF3IP2 TRAF5 TRAF6 TRAFD1 TRAM1 TRIM17 TRIM21 TRIM23 TRIM25 TRIM32 TRIM36 TRIM39 TRIM5 TRIP12 TRIP4 TSG101 TTC28 TTC36 TTF2 TUBA3C TUBA3D TUBGCP2 UBA1 UBA2 UBA6 UBAC1 UBAC2 UBAP1 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D4 UBE2E3 UBE2G2 UBE2J1 UBE2J2 UBE2L3 UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2V1 UBE2V2 UBE3A UBFD1 UBL7 UBQLN1 UBQLN2 UBQLN4 UBR4 UBR5 UBXN1 UBXN6 UBXN7 UCHL1 UCHL5 UEVLD UFD1 UIMC1 ULK1 UNC79 UNC93B3 USP1 USP10 USP11 USP12 USP13 USP14 USP16 USP19 USP21 USP22 USP24 USP25 USP27X USP28 USP3 USP30 USP31 USP32 USP33 USP34 USP35 USP36 USP37 USP38 USP4 USP40 USP42 USP45 USP46 USP47 USP48 USP5 USP53 USP54 USP6 USP7 USP8 USP9X USP9Y VCP VCPIP1 VPS28 VPS36 VPS37A VPS37C VPS50 WARS1 WBP2 WDR33 WDR48 WFDC8 WRNIP1 WWP1 WWP2 XIAP XPNPEP1 XRCC5 XRCC6 YAF2 YARS2 YIPF5 YOD1 YWHAB YWHAG YWHAZ ZBTB1 ZC3H12A ZCWPW2 ZFAND2B ZFAND3 ZFAND5 ZFAND6 ZFYVE9 ZHX1 ZNF148 ZNF213 ZNF451 ZNF705G ZNF716 ZNF792 ZNRF1 ZNRF2 ZRANB1 ZUP1	399 interacting genes: A2M ABI3 ABI3BP ABL1 ABL2 ACAP1 ADA ADAM12 ADAM15 ADRB1 ADRB2 AEBP1 AGR2 AGT AHSG AJUBA ALAS2 ALOX5 AMBP ANKRD13A ANKRD23 ANXA2 AP4S1 APCS APOH APP AR ARHGAP17 ARHGAP32 ARHGAP35 ARID5A ASAP1 ASAP2 AUNIP AXL B2M BCAR1 BCL2A1 BCR BLNK BPGM BTG1 C1orf94 C21orf58 C21orf91 CALD1 CASC3 CASP2 CBL CBLB CBLC CCDC28B CCL5 CD164 CD19 CD22 CD247 CD28 CD2AP CD72 CDC42 CDKN1B CFH CHRM4 CHRND CKS2 CLNK CLU COPB1 COX6A1 CPSF7 CRBN CRK CRKL CSF1R CSF3R CSN2 CTTN CUTA DAB2 DAG1 DCTN1 DCTN2 DDIT4L DDX17 DLGAP1 DNAJA3 DNAJB11 DNM1 DNM2 DOCK4 DPPA4 DRD3 DRD4 DTX1 DTX3 DVL2 E2F2 ECHS1 EFHC2 EGF EGFR ELK1 ENO1 EP300 EPHA2 EPHB1 EPHB2 EPHB6 EPOR EPS15 EPS8 ERBB2 ERBB3 ERBB4 ERRFI1 ESD ESR1 ETV6 FABP1 FASLG FCGR2A FCGR2B FGFR1 FGFR3 FH FHOD1 FLT1 FLT3 FLT4 FN1 FRS2 FRS3 FTH1 FTL FYN GAB1 GAB2 GAB3 GAREM1 GC GGN GHR GIT1 GPANK1 GRAP2 GRB7 GSTK1 H1-0 HCLS1 HELZ HIPK3 HNRNPC HNRNPK HOMEZ HP HRAS HSPA5 HTT IK IKZF3 IL2RB INCA1 INPP5D IRS1 IRS2 IRS4 ITGA2B ITGA6 ITGB4 ITIH4 ITK JAK1 JAK2 KDR KHDRBS1 KHDRBS2 KIAA0408 KIAA1549L KIF3A KIT KPNA2 KPRP KRT8 LAT LAT2 LAX1 LCP2 LIME1 LMO2 LNX1 LNX2 LY6G6F LZTS2 MAP1A MAP2 MAP4K1 MAP4K3 MAP4K5 MAPK1 MAPK12 MAPK14 MAPK9 MAPT MED19 MED28 MEI4 MERTK MET METTL27 MIA2 MICAL1 MLXIPL MS4A2 MSI2 MST1R MT-ATP8 MT-ND4 MTA1 MTA3 MUC1 MYG1 MYH11 MYH9 MYO18A MYOZ1 NADK NAP1L5 NCKIPSD NCL NEU3 NFYB NGFR NIF3L1 NKD2 NPM1 NTRK1 NUTM2F OCRL OLIG1 PACRGL PAG1 PAK1 PAK2 PAK4 PBXIP1 PCDHB5 PDCD6IP PDE4D PDE6G PDGFRB PHACTR4 PHC2 PHETA1 PIK3AP1 PIK3C2B PIK3CG PIK3R1 PIK3R2 PIK3R3 PLCG1 PLEKHA7 PNMA5 PNRC1 POLR1D POLR2A POMP PON2 PPP3CA PRAP1 PRKAB1 PRKAR1A PRNP PRR22 PRR5-ARHGAP8 PRRC2A PTK2 PTK2B PTPN1 PTPN11 PTPN12 PTPN22 PTPN6 PTPRA PTPRC PTPRE PXN RALGPS1 RAPGEF1 RAPSN RASA1 RBBP6 RBM33 RBP4 REL REPS1 REPS2 RET RHOU RIF1 RNF10 RNF208 RPS6KA1 SELL SF3A2 SF3B4 SH2B1 SH2B2 SH2B3 SH2D1A SH2D4A SH3BP2 SH3D19 SH3KBP1 SHANK3 SHB SHBG SHC1 SHC2 SHC3 SHC4 SHKBP1 SIGLEC7 SIT1 SKAP1 SLC1A2 SLX1A SNRNP200 SNTA1 SOCS1 SOCS7 SOS1 SOS2 SPATA2L SPRY1 SPRY2 SPTBN1 SRC SS18 STAMBP STK32C STRADB SYK SYN1 SYNCRIP SYNJ1 SYNJ2 SYP TBC1D3B TBC1D3G TCEAL8 TCERG1 TEK TF TFG TLE5 TNFRSF1A TNK2 TOM1L1 TP53BP2 TP63 TRAT1 TRIB3 TRIM27 TSC2 TSPAN2 TUB TXK TYRO3 UBA1 UBA52 UBC UQCC2 USP53 USP6NL USP8 VAV1 VAV2 VAV3 VIM VPS37C WAS WASF1 WASF2 WASL WBP11 WDFY3 WDR1 WDR44 WIPF1 WIPF2 YLPM1 ZAP70 ZBTB12 ZBTB7B ZMAT1 ZNF341 ZNF474 ZNF620
Entrez ID		7316	2885
HPRD ID		07038	00150
Ensembl ID		ENSG00000150991	ENSG00000177885
Uniprot IDs		P0CG48	B0LPF3 P62993
PDB IDs		1C3T 1CMX 1D3Z 1F9J 1FXT 1G6J 1GJZ 1NBF 1OGW 1Q5W 1S1Q 1SIF 1TBE 1UBI 1UBQ 1UD7 1XD3 1XQQ 1YX5 1YX6 1ZGU 1ZO6 2AYO 2BGF 2DEN 2FUH 2G45 2GBJ 2GBK 2GBM 2GBN 2GBR 2GMI 2HTH 2IBI 2J7Q 2JF5 2JRI 2JY6 2JZZ 2K25 2K6D 2K8B 2K8C 2KDF 2KHW 2KJH 2KLG 2KN5 2KX0 2L3Z 2LD9 2LVO 2LVP 2LVQ 2LZ6 2MBO 2MBQ 2MCN 2MI8 2MJ5 2MOR 2MRE 2MWS 2N2K 2NR2 2O6V 2OJR 2PE9 2PEA 2RR9 2RU6 2W9N 2WDT 2XEW 2Y5B 2Z59 2ZCB 2ZVN 2ZVO 3A33 3ALB 3AUL 3B08 3B0A 3BY4 3C0R 3DVG 3DVN 3EEC 3EFU 3EHV 3H7P 3H7S 3HM3 3I3T 3IFW 3IHP 3JSV 3JVZ 3JW0 3K9O 3K9P 3KVF 3KW5 3LDZ 3MHS 3MTN 3N30 3N32 3N3K 3NS8 3O65 3OFI 3OJ3 3OJ4 3ONS 3PRM 3PT2 3PTF 3Q3F 3RUL 3TMP 3U30 3UGB 3V6C 3V6E 3VFK 3VUW 3VUX 3VUY 3WXE 3WXF 3ZLZ 3ZNH 3ZNI 3ZNZ 4AP4 4AUQ 4BOS 4BOZ 4BVU 4DDG 4DDI 4DHJ 4DHZ 4FJV 4HK2 4HXD 4I6L 4I6N 4IG7 4IUM 4JQW 4K1R 4K7S 4K7U 4K7W 4KSK 4KSL 4LCD 4LDT 4MDK 4MM3 4MSM 4MSQ 4NQK 4UN2 4V3K 4V3L 4WZP 4XOK 4XOL 4ZQS 5A5B 5AF4 5AF5 5AF6 5AIT 5AIU 5B83 5C7J 5C7M 5E6J 5H07 5NL4 5NLF 5NLI 5NMC 5OE7 5OHV 5OXH 5OXI 5UDH 5WQ4 5ZQ3 5ZQ4 5ZQ5 5ZQ6 5ZQ7 6A43 6A44 6AQR 6B7M 6B7O 6EQI 6K2U 6KBE 6N13 6N6R 6NQA 6NXK 6OI4 6P5B 6Q00 6QML 6RYA 6S53 6SQR 6T7F 6T9L 6TNF 6TTU 6ULH 6UMP 6UMS 6UPU 6V5D 6VAE 6VAF 6VEN 6W9D 6W9R 6W9S 6WJD 7BXG	1AZE 1BM2 1BMB 1CJ1 1FHS 1FYR 1GCQ 1GFC 1GFD 1GHU 1GRI 1IO6 1JYQ 1JYR 1JYU 1QG1 1TZE 1X0N 1ZFP 2AOA 2AOB 2H46 2H5K 2HUW 2VVK 2VWF 2W0Z 3C7I 3IMD 3IMJ 3IN7 3IN8 3KFJ 3MXC 3MXY 3N7Y 3N84 3N8M 3OV1 3OVE 3S8L 3S8N 3S8O 3WA4 4P9V 4P9Z 5CDW 6ICG 6ICH 6SDF 6VK2 6WM1 6WO2
Enriched GO Terms of Interacting Partners?
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