TXK and ZNF792

Data Source:
BioGRID (two hybrid)

		TXK	ZNF792
Description		TXK tyrosine kinase	zinc finger protein 792
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cytokine Production Adaptive Immune Response Protein Phosphorylation Activation Of Phospholipase C Activity Integrin-mediated Signaling Pathway Regulation Of Gene Expression Regulation Of Platelet Activation Positive Regulation Of Interferon-gamma Production Peptidyl-tyrosine Autophosphorylation Tissue Regeneration Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation T Cell Receptor Signaling Pathway Positive Regulation Of Interferon-gamma-mediated Signaling Pathway	Regulation Of Transcription By RNA Polymerase II
Pathways		FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization	Generic Transcription Pathway
Drugs		Fostamatinib Zanubrutinib
Diseases
GWAS		Crohn's disease ( 23128233) Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) Platelet distribution width ( 32888494 27863252)	Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		38 interacting genes: CBY2 CCDC33 CCR5 CLNK CRK CTLA4 DOK2 DUSP6 EFHC2 EGFR ERBB2 ERBB3 ERBB4 FYN GRB10 GRB2 HOMEZ IKZF1 IKZF4 JRK KIT LCP2 MET NCK2 NELFCD PIK3R1 PRDM14 RBAK SH2D2A SOCS3 SOCS6 SRC STAP2 TNS4 YTHDC1 ZNF587 ZNF792 ZNF835	55 interacting genes: AQP1 BACH2 CCDC125 CCNC DVL3 ELOA EXOSC5 FAM161A FBL FHL5 GAS8 GOLGA6L9 HNRNPK KCTD12 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 MCC MID2 MTUS2 PRPF31 RBMY1F RBMY1J RNF4 SSX2IP TBC1D26 TLE5 TRIM41 TXK UBC ZBTB24 ZNF250 ZNF275 ZNF286A ZNF408 ZNF473 ZNF48 ZNF497 ZNF526 ZNF552 ZNF581 ZNF639 ZNF648 ZNF655 ZNF668 ZNF71 ZNF835 ZNF837 ZRANB1
Entrez ID		7294	126375
HPRD ID		02505	13430
Ensembl ID		ENSG00000074966	ENSG00000180884
Uniprot IDs		P42681	Q3KQV3
PDB IDs		2DM0
Enriched GO Terms of Interacting Partners?
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